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CNX-2006

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CNX-2006 Basic information

Product Name:
CNX-2006
Synonyms:
  • CNX-2006
  • N-[3-[[2-[[4-[[1-(2-Fluoroethyl)-3-azetidinyl]aMino]-2-Methoxyphenyl]aMino]-5-(trifluoroMethyl)-4-pyriMidinyl]aMino]phenyl]-2-propenaMide
  • 2-Propenamide, N-[3-[[2-[[4-[[1-(2-fluoroethyl)-3-azetidinyl]amino]-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-
  • N-[3-({2-[(4-{[1-(2-Fluoroethyl)-3-azetidinyl]amino}-2-methoxyphe nyl)amino]-5-(trifluoromethyl)-4-pyrimidinyl}amino)phenyl]acrylam ide
  • CS-1000
  • CNX2006; CNX 2006
  • N-(3-((2-((4-((1-(2-Fluoroethyl)azetidin-3-yl)amino)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide
  • CNX 2006 N-[3-[[2-[[4-[[1-(2-Fluoroethyl)-3-azetidinyl]amino]-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide
CAS:
1375465-09-0
MF:
C26H27F4N7O2
MW:
545.53
Product Categories:
  • Inhibitors
  • Aromatics, Agonist, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
1375465-09-0.mol
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CNX-2006 Chemical Properties

Density 
1.396±0.06 g/cm3(Predicted)
storage temp. 
Store at -20° C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml; Ethanol: 10 mg/ml
form 
A crystalline solid
pka
13.23±0.70(Predicted)
color 
White to gray
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CNX-2006 Usage And Synthesis

Uses

N-[3-[[2-[[4-[[1-(2-Fluoroethyl)-3-azetidinyl]amino]-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide, is a novel irreversible mutant-selective EGFR inhibitor.

CNX-2006Supplier

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