Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI) Chemical Properties

Melting point:

173.4-174.4 °C(Solv: ethanol (64-17-5))

Density 

1.32±0.1 g/cm3(Predicted)

pka

7.61±0.20(Predicted)

Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI) Usage And Synthesis

Uses

N4,3'',5''-Tribenzoyl,2''-deoxy-2''-methylene Cytidine is an impurity of Sofosbuvir (P839640); a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI)(863329-63-9)Related Product Information

• Sofosbuvir metabolites GS566500
• PSI 7411
• PSI-7977-13C-d3
• L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester
• Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI)
• Sofosbuvir
• Sofosbuvir IMpurity C 1337482-15-1
• Sofosbuvir Impurity 8
• (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
• BenzaMide, N-[1-(3,5-di-O-benzoyl-2-C-Methyl-β-D-arabinofuranosyl)-1,2-dihydro-2-oxo-4-pyriMidinyl]-
• Sofosbuvir Impurity
• 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione
• PSI 352707-13C,D3
• Sofosbuvir Impurity 32
• 2'-deoxy-2'-fluoro-2'-C-methyluridine
• PSI-6130 derivative
• ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
• Sofosbuvir IMpurity