(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione
(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Basic information
- Product Name:
- (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione
- Synonyms:
-
- (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione
- Fluticasone Related CoMpound B
- Fluticasone USP RC B
- Fluticasone Impurity 10(Fluticasone USP RC B)
- 6alpha,9alpha-Difluoro-11beta-hydroxy-16alpha-methyl-2',3,4'-trioxo-17alpha-spiro(androsta-1,4-diene-17,5'-(1,3)oxathiolane)
- (5R,6'S,8'S,9'R,10'S,11'S,13'S,14'S,16'R)-6',9'-difluoro-11'-hydroxy-10',13',16'-trimethylspiro[1,3-oxathiolane-5,17'-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene]-2,3',4-trione
- Fluticasone USP Related Compound B/Fluticasone Trioxo Impurity/6α,9α-Difluoro-11β-hydroxy-16α-methyl-2',3,4'-trioxo-17α-spiro(androsta-1,4-diene-17,5'-(1,3)oxathiolane)
- (5'R,6S,8S,9R,10S,11S,13S,14S,16R)
- CAS:
- 219719-95-6
- MF:
- C22H24F2O5S
- MW:
- 438.48
- Product Categories:
-
- Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
- Mol File:
- 219719-95-6.mol
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(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Chemical Properties
- Melting point:
- >125°C (dec.)
- Boiling point:
- 562.1±60.0 °C(Predicted)
- Density
- 1.43±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- pka
- 12.93±0.70(Predicted)
- color
- Off-White to Pale Beige
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(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Usage And Synthesis
Uses
An impurity of Fluticasone Propionate (F599500), a derivative of Flumethasone (F455000). An antiallergic; anti-asthmatic; anti-inflammatory. Fluticasone USP Related Compound B.
(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trioneSupplier
hubei PharmaStandard Co., Ltd. Gold
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- 027-19050701 13545374703
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J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
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Nanjing Chemlin Chemical Co., Ltd
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- 025-83697070
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Beijing Comparison Pharmaceutical Technology Co., Ltd
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- 010-010-52878169 15801002657
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Shanghai TaoSu Biochemical Technology Co., Ltd.
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- 021-33632979
- info@tsbiochem.com
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(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione(219719-95-6)Related Product Information
- Fluticasone
- Finasteride
- 11-Oxo Fluticasone Propionate
- Fluticasone
- Fluticasone Acetate
- Fluticasone
- 5-Chloromethyl 6a,9a-Difluoro-11-hydroxy-16a-methyl-3-oxo-17a-(propionyloxy)-androsta-1,4-diene-17-carbothioate
- (6α,11β,16α,17α)-(6'α,11'β,16'α,17'α)-17,17'-(Trithiodicarbonyl)bis[6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-androsta-1,4-dien-3-one
- DesfluoroMethyl Fluticasone Propionate Disulfide
- Fluticasone IMpurity
- (1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)-
- (6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid
- Fluticasone propionate
- Fluticasone propionate-d5
- Fluticasone EP IMpurity B
- FLUTICASONE PROPIONATE INTERMEDIATE
- 5-Iodomethyl 6a,9a-Difluoro-11-hydroxy-16a-methyl-3-oxo-17a-(propionyloxy)-androsta-1,4-diene-17-carbothioate
- Ticabesone Propionate