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FMOC-7-AMINO-HEPTANOIC ACID

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FMOC-7-AMINO-HEPTANOIC ACID Basic information

Product Name:
FMOC-7-AMINO-HEPTANOIC ACID
Synonyms:
  • 7-Aminoheptanoic acid, N-FMOC protected
  • 7-(FMOC-AMINO)HEPTANOIC ACID 98+%
  • 7-(Fmoc-amino)enanthic acid, 7-(Fmoc-amino)heptanoic acid
  • FMoc-7-AMinoheptanoic acid FMoc-7-AMinoheptanoic acid
  • 7-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)heptanoic acid
  • N-Fmoc-7-amino-heptanoic acid
  • 7-Aminoheptanoic acid, N-FMOC protected 98%
  • 7-[N-(9-Fluorenylmethoxycarbonyl)amino]heptanoic acid
CAS:
127582-76-7
MF:
C22H25NO4
MW:
367.44
Product Categories:
  • Unusual amino acids
Mol File:
127582-76-7.mol
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FMOC-7-AMINO-HEPTANOIC ACID Chemical Properties

Boiling point:
590.0±33.0 °C(Predicted)
Density 
1.191±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
pka
4.77±0.10(Predicted)
form 
Powder
color 
White
Water Solubility 
Slightly soluble in water.
CAS DataBase Reference
127582-76-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2924297099

MSDS

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FMOC-7-AMINO-HEPTANOIC ACID Usage And Synthesis

Description

Fmoc-7-amino-heptanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

White powder

Uses

7-(Fmoc-amino)heptanoic acid is used as pharmaceutical intermediates.

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