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Treprostinil intermediate

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Treprostinil intermediate Basic information

Product Name:
Treprostinil intermediate
Synonyms:
  • Treprostinil intermediate
  • (alphaS,1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-5-methoxy-alpha-pentyl-1H-benz[f]indene-1-propanol
  • (1R,2R,3aS,9aS)-1-(2-Hydroxyoctyl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol
  • (1R,2R,3aS,9aS)-1-((S)-3-hydroxyoctyl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol
  • (1R,2R,3aS,9aS)-1-((S,E)-3-hydroxyoct-1-en-1-yl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol
  • Descarboxy Treprostinil
  • Treprostinil Impurity 2
  • Treprostinil Impurity 1
CAS:
101692-01-7
MF:
C22H34O3
MW:
346.5
Mol File:
101692-01-7.mol
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Treprostinil intermediate Chemical Properties

Melting point:
71-72 °C
Boiling point:
509.0±50.0 °C(Predicted)
Density 
1.062±0.06 g/cm3(Predicted)
pka
15.10±0.40(Predicted)
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Treprostinil intermediate Usage And Synthesis

Uses

Descarboxy Treprostinil is an impurity in the synthesis of Treprostinil (T719500), Synthetic analog of Prostacyclin (P839060). Antihypertensive. Treprostinil, marketed under the trade name Remodulin is a medication used to treat pulmonary arterial hypertension (PAH).

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