Pyridine hydrofluoride Chemical Properties

Boiling point:

50°C 1mm

Density 

1.1 g/mL at 20 °C(lit.)

Flash point:

50°C/1mm

storage temp. 

-20°C Freezer, Under inert atmosphere

solubility 

sol CH2Cl2, MeCN, Et2O, THF, toluene, sulfolane.

form 

Liquid

color 

Clear pale yellow to light brown

Sensitive 

Moisture Sensitive

BRN 

4750151

CAS DataBase Reference

32001-55-1(CAS DataBase Reference)

EPA Substance Registry System

Pyridine hydrofluoride (32001-55-1)

Safety Information

Hazard Codes 

T+,C

Risk Statements 

26/27/28-35-34

Safety Statements 

26-28-36/37/39-45-27

RIDADR 

UN 1790 8/PG 1

WGK Germany 

2

F 

3-10

TSCA 

T

HazardClass 

8

PackingGroup 

II

HS Code 

29333999

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Pyridine hydrofluoride Usage And Synthesis

Description

Pyridine hydrofluoride has a convenient, less volatile form of anhydrous HF with enhanced nucleophilicity.

Chemical Properties

clear pale yellow to light brown liquid

Uses

Pyridinium Poly(hydrogenfluoride) is used in the synthesis of analogues of antimitotic natural product curacin A. It is also an effective fluorinating agent.

Synthesis

?Pyridine hydrofluoride is prepared by condensation of anhydrous Hydrogen Fluoride into Pyridine at -78 °C, followed by gradual warming to rt; caution: highly exothermic.

Pyridine hydrofluoride(32001-55-1)Related Product Information

• Hydrogen
• FLUORIDE STANDARD
• Hydrogen fluoride
• Pyridine
• Hydrogen Sulfide
• Ammonium hydrogen difluoride
• Sodium hydrogen difluoride
• Potassium hydrogen fluoride
• Aluminum fluoride
• Pyridine hydrofluoride,HF-Pyridine, Pyridine hydrofluoride
• Hydrogen peroxide
• HYDROGEN CYANIDE
• 4-AMINO-3-CHLORO-2,5,6-TRIFLUOROPYRIDINE
• 2,6-Difluoropyridine
• 4-Amino-3,5-dichloro-2,6-difluoropyridine
• 7-TRIFLUOROMETHYL-4-QUINOLINETHIOL
• Pentafluoropyridine
• 3-Fluoropyridine