4,10-DIOXATRICYCLO[5.2.1.0(2,6)]DEC-8-ENE-3,5-DIONE Chemical Properties

Melting point:

118 °C

Boiling point:

372.0±42.0 °C(Predicted)

Density 

1.540±0.06 g/cm3(Predicted)

storage temp. 

-20°C, sealed storage, away from moisture

form 

Solid

color 

White to off-white

InChI

InChI=1S/C8H6O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h1-6H

InChIKey

QQYNRBAAQFZCLF-UHFFFAOYSA-N

SMILES

C1(=O)C2C(C3OC2C=C3)C(=O)O1

EPA Substance Registry System

4,7-Epoxyisobenzofuran-1,3-dione, 3a,4,7,7a-tetrahydro- (5426-09-5)

4,10-DIOXATRICYCLO[5.2.1.0(2,6)]DEC-8-ENE-3,5-DIONE Usage And Synthesis

Uses

4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

4,10-DIOXATRICYCLO[5.2.1.0(2,6)]DEC-8-ENE-3,5-DIONE(5426-09-5)Related Product Information

• 7-OXABICYCLO[2.2.1]HEPTANE
• 4,10-DIOXATRICYCLO[5.2.1.0(2,6)]DEC-8-ENE-3,5-DIONE
• TETRAHYDRO-3-FUROIC ACID
• EXO-3,6-EPOXY-1,2,3,6-TETRAHYDROPHTHALIC ANHYDRIDE
• (R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID
• cis-1,2,3,6-Tetrahydrophthalic anhydride
• Methyl (R)-(-)-3-hydroxybutyrate
• (R)-Tetrahydro-3-furancarboxylic acid
• TETRAHYDROFURAN-3-CARBOXALDEHYDE 98
• Methyl (S)-(+)-3-hydroxybutyrate
• 2-CYCLOHEXEN-1-OL
• 1,2,3,6-Tetrahydrophthalic anhydride
• 4,7-epoxy-3a,4,7,7a-tetrahydroisobenzofuran-1(3h)-one
• NAPHTHENIC ACID
• (S)-Tetrahydro-3-furancarboxylic acid
• 3-ALLYLOXYPROPIONIC ACID
• 3-CYCLOHEXENE-1-CARBOXYLIC ACID METHYL ESTER
• ALLYLSUCCINIC ANHYDRIDE