9,9-Diphenylfluorene-2-Boronic acid pinacol ester Chemical Properties

Melting point:

198.0 to 202.0 °C

Boiling point:

556.2±29.0 °C(Predicted)

Density 

1.17±0.1 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

powder to crystal

color 

White to Almost white

Safety Information

HS Code 

2934.99.4400

9,9-Diphenylfluorene-2-Boronic acid pinacol ester Usage And Synthesis

Synthesis

The general procedure for the synthesis of 2-(9,9-diphenyl-9H-fluoren-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane from biphenylpinacol ester and 2-bromo-9,9-diphenylfluorene was carried out in the following manner: in a single-necked round-bottomed flask, 2-bromo-9,9-diphenyl-9H-fluorene (40 g, 100.67 mmol), biphenylpinacol ester (51.1 g, 201.34 mmol), PdCl2(dppf) (2.2 g, 3.02 mmol), KOAc (29.6 g, 302.01 mmol) and DMF (400 ml) were mixed and the reaction was carried out at reflux. Upon completion of the reaction, the mixture was extracted with dichloromethane and the organic phase was dried with anhydrous MgSO4, followed by removal of the solvent DMF under reduced pressure by rotary evaporator.The crude product was purified by column chromatography (silica gel as stationary phase, eluent hexane and dichloromethane in a 1:1 ratio, v/v/v/v) to afford the white solid product 2-(9,9-diphenyl-9H-fluoren-2-yl)-4,4,5,5-tetramethyl- 1,3,2-dioxaborolane (41 g, 91% yield).

References

[1] Patent: CN105408333, 2016, A. Location in patent: Paragraph 0212; 0213; 0214

9,9-Diphenylfluorene-2-Boronic acid pinacol ester(462128-39-8)Related Product Information

• 2-(9H-Fluoren-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
• 1,3,2-DIOXABOROLANE, 2-(9,9-DIMETHYL-9H-FLUOREN-2-YL)-4,4,5,5-TETRAMETHYL
• 9,9'-spirobi[fluorene]-2,2'-diyldiboronic acid
• (2,7-BIS(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-9,9-DIOCTYLFLUORENE)
• 9,9-DiMethylfluorene-3-boronic acid pinacol ester
• 4,4,5,5-tetramethyl-2-(9,9'-spirobi[9H-fluoren]-4-yl)-1,3,2-Dioxaborolane
• 9,9-Spirodifluorene-2-Boronic acid pinacol ester
• 4 - boric acid pinacol ester - 9, 9 - dimethyl fluorene
• 9,9-Spirodifluorene-3-Boronic acid pinacol ester
• 9,9-diphenyl-9H-fluoreN-4-ylboronicacid
• 4-Pinacol ester-9,9-dipehnylfluorene
• 1,3,2-DIOXABOROLANE, 2,2'-(9,9-DIMETHYL-9H-FLUORENE-2,7-DIYL)BIS[4,4,5,5-TETRAMETHYL]
• 9,9-diphenyl-fluoren-3-boronic acid pinacol ester