(9R)-6′-Methoxycinchonan-9-amine trihydrochloride Chemical Properties

alpha 

+62.3° (c=1.0, H2O)

form 

Powder

color 

white to off-white

optical activity

[α]/D +4.0±1.0°, c = 1 in 0.1 M HCl

Stability:

store cold

Safety Information

WGK Germany 

3

(9R)-6′-Methoxycinchonan-9-amine trihydrochloride Usage And Synthesis

Reaction

1. Aza-Michael reactions on α,β-unsaturated ketones.
2. Epoxidation of α,β-unsaturated ketones.
3. Epoxidation of α,β-unsaturated aldehydes.
4. Nitrocyclopropanation of α,β-unsaturated ketones.
5. Diels-Alder reaction.
6. Intramolecular aldolization of diketones.
7. Friedel-Crafts alkylation of indoles with α,β-unsaturated ketones.
8. Friedel-Crafts/amination cascade reactions with a-substituted α,β-unsaturated aldehydes.
9. Aziridination of acyclic α,β-unsaturated ketones.
10. Aziridination of cyclic α,β-unsaturated ketones.
11. Double Michael cascade process.
12. α-fluorination of cyclic ketones. 

(9R)-6′-Methoxycinchonan-9-amine trihydrochloride (1391506-12-9)Related Product Information

• Quinine
• (9R)- 9-isothiocyanato-6'-Methoxy-Cinchonan
• (9R)-9-aMino-Cinchonan-6'-ol
• (9S)- 10,11-dihydro-Cinchonan-6',9-diol
• (9R)-6'-Cinchonan-9-amine Trihydrochloride
• (9S)-9-(9-phenanthrenyloxy)-Cinchonan-6'-ol
• (9R)-9-aMino-10,11-dihydro-Cinchonan-6'-ol
• (8α,9S)- 9-isothiocyanato-6'-Methoxy-Cinchonan
• (9S)- 9-(phenylMethoxy)-Cinchonan-6'-ol
• O-Desmethyl Quinidine