2-Keto-3-methylbutyric acid-13C5 sodium salt Chemical Properties

Melting point:

227-230°C

solubility 

DMSO (Slightly), Water (Slightly)

form 

Solid

color 

White to Off-White

CAS Number Unlabeled

3715-29-5

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-37/38-41

Safety Statements 

26-36/37/39

WGK Germany 

3

2-Keto-3-methylbutyric acid-13C5 sodium salt Usage And Synthesis

Uses

Sodium 3-methyl-2-oxobutanoate-13C5 is the 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] MAAS WK, et al. alpha-Ketoisovaleric acid, a precursor of pantothenic acid in Escherichia coli. J Bacteriol. 1953 Apr;65(4):388-93. DOI:10.1128/jb.65.4.388-393.1953
[3] Schauder P, et al. Oral administration of alpha-ketoisovaleric acid or valine in humans: blood kinetics and biochemical effects. J Lab Clin Med. 1984 Apr103(4):597-605. PMID:6366097
[4] Coitinho AS, et al. Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain Res. 2001 Mar 9894(1):68-73. DOI:10.1016/s0006-8993(00)03321-7

2-Keto-3-methylbutyric acid-13C5 sodium salt (1173018-24-0)Related Product Information

• α-Keto Isovaleric Acid Sodium Salt Dimethyl-13C2
• α-Keto Isovaleric Acid Sodium Salt 13C4, D4
• 2-KETO-3-METHYLBUTYRIC ACID-13C5, 3-D1 SODIUM SALT
• Sodium 3-methyl-2-oxobutanoate
• α-Keto Isovaleric Acid Sodium Salt 3-Methyl-13C, D4