Basic information description Chemical properties Application and Synthesis Improvement of UV - 9 Production Process Safety Supplier Related
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Oxybenzone

Basic information description Chemical properties Application and Synthesis Improvement of UV - 9 Production Process Safety Supplier Related

Oxybenzone Basic information

Product Name:
Oxybenzone
Synonyms:
  • component of Presun 29
  • component of Presun 30
  • Cyasorb uv 9
  • Cyasorb uv 9 light absorber
  • cyasorbuv9
  • Escalol 567
  • Eusolex 4360
  • Lankromark LE296
CAS:
131-57-7
MF:
C14H12O3
MW:
228.24
EINECS:
205-031-5
Product Categories:
  • UVINUL M40
  • Aromatic Benzophenones & Derivatives (substituted)
  • Industrial/Fine Chemicals
  • Additives for Plastic
  • Organics
  • 131-57-7
Mol File:
131-57-7.mol
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Oxybenzone Chemical Properties

Melting point:
62-64 °C(lit.)
Boiling point:
150-160 °C5 mm Hg(lit.)
Density 
1,3 g/cm3
vapor pressure 
0.001Pa at 25℃
refractive index 
1.5805 (estimate)
Flash point:
216°C
storage temp. 
2-8°C
solubility 
95% ethanol: soluble50mg/mL, clear, colorless
form 
Crystalline Powder
pka
7.56±0.35(Predicted)
color 
White to light yellow
Odor
ylsh. cryst., rose-like odor
Water Solubility 
<0.1 g/100 mL at 20 ºC
Merck 
14,6954
BRN 
1913145
InChIKey
DXGLGDHPHMLXJC-UHFFFAOYSA-N
LogP
3.45 at 40℃
CAS DataBase Reference
131-57-7(CAS DataBase Reference)
NIST Chemistry Reference
Oxybenzone(131-57-7)
EPA Substance Registry System
2-Hydroxy-4-methoxybenzophenone (131-57-7)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37
RIDADR 
UN 3077 9/PG III
WGK Germany 
2
RTECS 
DJ1575000
TSCA 
Yes
HazardClass 
9
PackingGroup 
III
HS Code 
29145000
Hazardous Substances Data
131-57-7(Hazardous Substances Data)
Toxicity
LD50 orally in rats: >12.8 g/kg (Lewerenz)

MSDS

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Oxybenzone Usage And Synthesis

description

Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.

Chemical properties

light yellow crystalline powder, soluble in ethanol, acetone and other organic solvents, insoluble in water.

Application and Synthesis

UV-9 is a light yellow or white crystalline powder, also known as sunscreen 2, BP-3, suitable for polyvinyl chloride, polyvinylidene chloride, polymethyl methacrylate , unsaturated polyester, ABS resin and cellulose resin and other plastics, the maximum absorption wavelength range of 280-340 nm, the general amount of 0.1-1.5%, good thermal stability, does not decompose at 200 ℃. This product hardly absorb visible light, it applies to light-colored transparent products. This product can also be used for paints and synthetic rubber. For the broad-spectrum UV absorbers, with high absorption rate, non-toxic, non-teratogenic effect, light, thermal stability. UV-9 can absorb UV-A and UV-B together, is the US FDA approved Class I sunscreen and being used with a higher frequency in the US and European countries. UV-9 is widely used in sunscreen cream, cream, honey, lotion, oil and other sunscreen cosmetics, but also as a product from the photosensitive and discoloration of the anti-discoloration agent. In addition, it is usually used for PVC and unsaturated polyester and many other fields, because UV-9 has good compatibility with many kinds of plastics and resins.

Improvement of UV - 9 Production Process

Using mixed acid as catalyst, trichloromethylbenzene and resorcinol were condensed into intermediate 2,4-dihydroxydiphenyl ketone in aqueous phase, and then the catalyst was treated with phase transfer catalyst, etherification of the target product UV-9.

Chemical Properties

white to light yellow crystalline powder

Uses

ultraviolet screen

Uses

Oxybenzone is an organic compound used in sunscreens. Oxybenzone is used as an ingredient in sunscreen and other cosmetics because it absorbs UVB and short-wave UVA (ultraviolet) rays. Oxybenzone was one of the first compounds incorporated into sunscreen formulations to offer enhanced UVA protection because its absorption spectrum extends to less than 350 nm.

Uses

Sunscreen. UV stabilizer

Uses

Ultraviolet light absorber and stabilizer, especially in plastics and paints.

Uses

benzophenone-3 (oxybenzone) is an oil-soluble uV absorber and filter with absorption rates within the uVA and uVB peak ranges. It has an approved usage level of up to 6 percent in the united States and 10 percent in the european union. Benzophenone-3 enhances SPF and is popular among sunscreen formulators given a concern over potential safety problems associated with more traditional sunscreen chemicals. However, some reports associate it with causing photocontact allergy. It is considered a non-comedogenic raw material.

Uses

oxybenzone (benzophenone-3) is the drug name for an FDAapproved uV filter and absorber.

Preparation

Preparation by partial methylation of 2,4- dihydroxy-benzophenone,
? with methyl iodide in the presence of sodium hydroxide;
? with a methyl halide;
? with dimethyl sulfate in the presence of sodium hydroxide or alkaline solution.

Definition

ChEBI: A hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively.

brand name

Uvinul M40 (BASF).

Synthesis Reference(s)

Tetrahedron, 42, p. 885, 1986 DOI: 10.1016/S0040-4020(01)87495-0

General Description

White to off-white or light yellow powder.

Air & Water Reactions

Insoluble in water.

Fire Hazard

Flash point data for Oxybenzone are not available; however, Oxybenzone is probably combustible.

Flammability and Explosibility

Non flammable

Contact allergens

BZP-3 is used as a direct sunscreen agent and in antiaging creams. Allergic reactions have been reported. Cross-reactivity is expected in an average of one in four patients photoallergic to ketoprofen.

Safety Profile

Poison by intraperitoneal route. Mddly toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Oxybenzone Preparation Products And Raw materials

Raw materials

Preparation Products

OxybenzoneSupplier

Jobachem Suzhou Co., Ltd Gold
Tel
0512-62927368; 18136961057
Email
min.li@jobachem.com
Products Intro
Product Name:2-Hydroxy-4-Methoxy Benzophenone; BP-3
CAS:131-57-7
Purity:0.99 Package:25kg/drum
Lianyungang Shenghe Biotechnology Co., Ltd. Gold
Tel
0518-87108777 13585296001
Email
haizaofu@163.com
Products Intro
Product Name:HMB
Tianjin Zhongxin Chemtech Co., Ltd.
Tel
022-66880623
Email
sales@tjzxchem.com
Products Intro
Product Name:2-Hydroxy-4-Methoxy Benzophenone
CAS:131-57-7
Purity:98% Package:20KG Drum
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Products Intro
Product Name:2-Hydroxy-4-methoxybenzophenone, 98%
CAS:131-57-7
Purity:98% Package:100G;25G;500G
Changzhou Sunchem Pharmaceutical Chemical Material Co.,Ltd.
Tel
0519-85195575 15861192208
Email
850305@sunkechem.com
Products Intro
Product Name:UV-9
CAS:131-57-7