UV absorber UV-9 Chemical Properties

Melting point:

62-64 °C(lit.)

Boiling point:

150-160 °C5 mm Hg(lit.)

Density 

1,3 g/cm³

vapor pressure 

0.001Pa at 25℃

refractive index 

1.5805 (estimate)

Flash point:

216°C

storage temp. 

2-8°C

solubility 

95% ethanol: soluble50mg/mL, clear, colorless

form 

Crystalline Powder

pka

7.56±0.35(Predicted)

color 

White to light yellow

Odor

ylsh. cryst., rose-like odor

Water Solubility 

<0.1 g/100 mL at 20 ºC

Merck 

14,6954

BRN 

1913145

InChIKey

DXGLGDHPHMLXJC-UHFFFAOYSA-N

LogP

3.45 at 40℃

CAS DataBase Reference

131-57-7(CAS DataBase Reference)

NIST Chemistry Reference

Oxybenzone(131-57-7)

EPA Substance Registry System

2-Hydroxy-4-methoxybenzophenone (131-57-7)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37

RIDADR 

UN 3077 9/PG III

WGK Germany 

2

RTECS 

DJ1575000

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29145000

Hazardous Substances Data

131-57-7(Hazardous Substances Data)

Toxicity

LD50 orally in rats: >12.8 g/kg (Lewerenz)

MSDS

• Language:English Provider:2-Hydroxy-4-methoxybenzophenone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

UV absorber UV-9 Usage And Synthesis

description

Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.

Chemical properties

light yellow crystalline powder, soluble in ethanol, acetone and other organic solvents, insoluble in water.

Application and Synthesis

UV-9 is a light yellow or white crystalline powder, also known as sunscreen 2, BP-3, suitable for polyvinyl chloride, polyvinylidene chloride, polymethyl methacrylate , unsaturated polyester, ABS resin and cellulose resin and other plastics, the maximum absorption wavelength range of 280-340 nm, the general amount of 0.1-1.5%, good thermal stability, does not decompose at 200 ℃. This product hardly absorb visible light, it applies to light-colored transparent products. This product can also be used for paints and synthetic rubber. For the broad-spectrum UV absorbers, with high absorption rate, non-toxic, non-teratogenic effect, light, thermal stability. UV-9 can absorb UV-A and UV-B together, is the US FDA approved Class I sunscreen and being used with a higher frequency in the US and European countries. UV-9 is widely used in sunscreen cream, cream, honey, lotion, oil and other sunscreen cosmetics, but also as a product from the photosensitive and discoloration of the anti-discoloration agent. In addition, it is usually used for PVC and unsaturated polyester and many other fields, because UV-9 has good compatibility with many kinds of plastics and resins.

Improvement of UV - 9 Production Process

Using mixed acid as catalyst, trichloromethylbenzene and resorcinol were condensed into intermediate 2,4-dihydroxydiphenyl ketone in aqueous phase, and then the catalyst was treated with phase transfer catalyst, etherification of the target product UV-9.

Chemical Properties

white to light yellow crystalline powder

Uses

ultraviolet screen

Uses

Oxybenzone is an organic compound used in sunscreens. Oxybenzone is used as an ingredient in sunscreen and other cosmetics because it absorbs UVB and short-wave UVA (ultraviolet) rays. Oxybenzone was one of the first compounds incorporated into sunscreen formulations to offer enhanced UVA protection because its absorption spectrum extends to less than 350 nm.

Uses

Sunscreen. UV stabilizer

Uses

Ultraviolet light absorber and stabilizer, especially in plastics and paints.

Uses

benzophenone-3 (oxybenzone) is an oil-soluble uV absorber and filter with absorption rates within the uVA and uVB peak ranges. It has an approved usage level of up to 6 percent in the united States and 10 percent in the european union. Benzophenone-3 enhances SPF and is popular among sunscreen formulators given a concern over potential safety problems associated with more traditional sunscreen chemicals. However, some reports associate it with causing photocontact allergy. It is considered a non-comedogenic raw material.

Uses

oxybenzone (benzophenone-3) is the drug name for an FDAapproved uV filter and absorber.

Preparation

Preparation by partial methylation of 2,4- dihydroxy-benzophenone,
? with methyl iodide in the presence of sodium hydroxide;
? with a methyl halide;
? with dimethyl sulfate in the presence of sodium hydroxide or alkaline solution.

Definition

ChEBI: A hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively.

brand name

Uvinul M40 (BASF).

Synthesis Reference(s)

Tetrahedron, 42, p. 885, 1986 DOI: 10.1016/S0040-4020(01)87495-0

General Description

White to off-white or light yellow powder.

Air & Water Reactions

Insoluble in water.

Fire Hazard

Flash point data for Oxybenzone are not available; however, Oxybenzone is probably combustible.

Flammability and Explosibility

Non flammable

Contact allergens

BZP-3 is used as a direct sunscreen agent and in antiaging creams. Allergic reactions have been reported. Cross-reactivity is expected in an average of one in four patients photoallergic to ketoprofen.

Safety Profile

Poison by intraperitoneal route. Mddly toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

UV absorber UV-9(131-57-7)Related Product Information

• BENZOYL ISOCYANATE
• 3-Methylbenzophenone
• Benzophenone
• Benzophenone imine
• 2,3,4-Trihydroxybenzoic acid
• 2-Methylbenzophenone
• 2,2',4,4'-Tetrahydroxybenzophenone
• 4,4'-Dimethylbenzophenone
• 4-Methylbenzophenone
• Benzoyl peroxide
• Benzoyl chloride
• CHLOROPHOSPHONAZO III
• 4-Hydroxybenzophenone
• 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone
• 4-Methoxybenzophenone
• Bisoctrizole
• Benazol P
• tetraethyl 2,2'-(1,4-phenylenedimethylidyne)bismalonate