Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  API >  Nervous system drugs >  Antidepressants, Antimanics drugs >  HEMATOPORPHYRIN DIHYDROCHLORIDE

HEMATOPORPHYRIN DIHYDROCHLORIDE

Basic information Safety Supplier Related

HEMATOPORPHYRIN DIHYDROCHLORIDE Basic information

Product Name:
HEMATOPORPHYRIN DIHYDROCHLORIDE
Synonyms:
  • 21h,23h-porphine-2,18-dipropanoicacid,7,12-bis(1-hydroxyethyl)-3,8,13,17-tetr
  • 21h,23h-porphine-2,18-propanoicacid,7,12-bis(1-hydroxyethyl)-3,8,13,17-tetr
  • 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-2,18-porphinedipropionicacid
  • acido1,3,5,8-tetrametil-2,4-bis(idrossietil)porpfina-6,7-dipropionicodiclor
  • ematoporfirina
  • HEMATOPORPHYRIN IX DIHYDROCHLORIDE
  • HEMATOPORPHYRIN DIHYDROCHLORIDE
  • HAEMATOPORPHYRIN DIHYDROCHLORIDE
CAS:
17696-69-4
MF:
C34H39ClN4O6
MW:
635.16
EINECS:
241-699-4
Product Categories:
  • Natural Porphyrins and Derivitives
  • Porphyrins
  • Miscellaneous Biochemicals
  • Biochemistry
  • porphine (porphyrin) ligand
Mol File:
17696-69-4.mol
More
Less

HEMATOPORPHYRIN DIHYDROCHLORIDE Chemical Properties

storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Very Dark Red
Water Solubility 
Insoluble in water. Soluble in pyridine (5%).
Merck 
14,4636
BRN 
78957
Stability:
Hygroscopic
EPA Substance Registry System
21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, dihydrochloride (17696-69-4)
More
Less

Safety Information

Risk Statements 
33
RTECS 
TS5505000
TSCA 
Yes
Toxicity
mouse,LD50,intraperitoneal,169mg/kg (169mg/kg),BEHAVIORAL: TREMORBEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY),Bollettino Chimico Farmaceutico. Vol. 117, Pg. 145, 1978.

MSDS

  • Language:English Provider:ALFA
More
Less

HEMATOPORPHYRIN DIHYDROCHLORIDE Usage And Synthesis

Description

Hematoporphyrin is a photosensitizer. Hematoporphyrin (3 μM) increases oxygen consumption and decreases the respiratory control ratio (RCR) in irradiated isolated rat liver mitochondria. It induces DNA breaks in cell-free assays, but not in human HeLa cervical cancer cells, in a light-dependent manner when used at a concentration of 6 μM. Hematoporphyrin (12 μM) decreases the survival of irradiated, but not non-irradiated, HeLa cells. Hematoporphyrin (5 mg/kg) decreases growth of subcutaneous Yoshida AH-130 hepatoma tumors in rats when administered with radiation.

Uses

Endogenous porphyrin formed by the acid hydrolysis of hemoglobin. It is employed as an active pharmaceutical intermediate.

HEMATOPORPHYRIN DIHYDROCHLORIDESupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Email
market03@meryer.com
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Email
sales@BioChemBest.com
Alfa Aesar
Tel
400-6106006
Email
saleschina@alfa-asia.com
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com