3-METHYL-L-HISTIDINE Chemical Properties

Melting point:

248～252℃

alpha 

+12.0～+18.0°(20℃/D)(c=2,dil.HCl)

Boiling point:

298.47°C (rough estimate)

Density 

1.37

refractive index 

1.5950 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

PBS (pH 7.2): 10 mg/ml

form 

A crystalline solid

pka

2.04±0.10(Predicted)

color 

White to off-white

optical activity

-25.818 (H2O)

Stability:

Hygroscopic

CAS DataBase Reference

368-16-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

3-METHYL-L-HISTIDINE Usage And Synthesis

Chemical Properties

White to off-white powder

Uses

3-Methyl-L-histidine is a potential compound to be used as a treatment with pharmacological PPARα agonists to stimulate the ubiquitin proteasome pathway and myofibrillar protein breakdown in skeleta l muscle of rodents.

Definition

ChEBI: A L-histidine derivative that is L-histidine substituted by a methyl group at position 3 on the imidazole ring.

Biochem/physiol Actions

3-Methyl-L-histidine is a non-proteinogenic amino acid and an index of muscle breakdown.

3-METHYL-L-HISTIDINE(368-16-1)Related Product Information

• 1-Methyl-L-histidine
• L-Histidine
• Methyl L-histidinate dihydrochloride
• H-HIS(BZL)-OH
• H-His(Trt)-OMe · HCl
• H-His(Trt)-OH
• 3-METHYL-L-HISTIDINE
• N-Boc-N'-benzyloxymethyl-L-histidine
• L-ANSERINE NITRATE
• FMOC-HIS(3-BOM)-OH
• Fmoc-His(Trt)-OH
• N-Boc-1-phenylmethyl-D-histidine
• N-Fmoc-N'-trityl-D-histidine
• N-Fmoc-N'-Trityl-L-histidine pentafluorophenyl ester
• Boc-His(Trt)-OH
• 1-Phenylmethyl-L-histidine methyl ester monohydrochloride
• N'-Methyl-L-histidine methyl ester
• FMOC-D-HIS(MTT)-OH