Pyridine sulfur trioxide Chemical Properties

Melting point:

~160 °C

storage temp. 

Store below +30°C.

solubility 

Soluble in polar organic solvents.

form 

Powder

color 

White to beige

Water Solubility 

reacts

Sensitive 

Moisture Sensitive

BRN 

3704116

InChI

InChI=1S/C5H5N.O3S/c1-2-4-6-5-3-1;1-4(2)3/h1-5H;

InChIKey

UDYFLDICVHJSOY-UHFFFAOYSA-N

SMILES

C1=CC=NC=C1.S(=O)(=O)=O

CAS DataBase Reference

26412-87-3(CAS DataBase Reference)

EPA Substance Registry System

Pyridine sulfur trioxide (26412-87-3)

Safety Information

Hazard Codes 

C

Risk Statements 

22-34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

F 

3-10-21

Autoignition Temperature

>350 °C

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29420000

Toxicity

LD50 orally in Rabbit: 500 - 2000 mg/kg

MSDS

• Language:English Provider:Pyridine sulfur trioxide
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Pyridine sulfur trioxide Usage And Synthesis

Chemical Properties

white solid

Uses

Sulfur trioxide-pyridine complex is used for sulfations of alcohols, sulfonations, deoxygenations and other reductions, oxidations with dimethyl sulfoxide. It is also used as a source of sulfur trioxide especially in the preparation of sulfate esters. Further, it is used as an activating electrophile in a Parikh-Doering oxidation. In addition to this, it is also used in the preparation and anticoagulation test of sulfated silk fibroin.

Uses

Pyridine-Sulfur Trioxide Complex is used in the sulfation of squid ink polysaccharides (SIPs) as a potential candidate compound for the prevention of tumor metastasis. Pyridine-Sulfur Trioxide Complex is also used in the preparation and anticoagulation test of sulfated silk fibroin.

Uses

Usually used for sulfations of alcohols, sulfonations, deoxygenations and other reductions, oxidations with DMSO.

Purification Methods

Wash the solid with a little CCl4, then H2O to remove traces of pyridine sulfate, and dry it over P2O5. [Baumgarten Chem Ber 59 1166 1926, Olah et al. Synthesis 59 1979, Beilstein 20/5 V 184].

Pyridine sulfur trioxide(26412-87-3)Related Product Information

• Diantimony trioxide
• Sulfur trioxide
• Pyridine
• INTERMEDIATES
• N-(Trimethylsilyl)imidazole
• 2-Pyridinecarboxaldehyde
• Pyridine hydrochloride
• 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
• Pyridinium tribromide
• Pyridine hydrobromide
• Pyridine-N-oxide
• Pyridine-4-boronic acid
• Sulfur
• 2,4-PENTANEDIONE, SILVER DERIVATIVE
• SALCOMINE
• COBALT(II) ACETYLACETONATE
• Cupric acetylacetonate
• N-BUTYLISOCYANIDE
• Sulfur Trioxide Pyridine Complex