4-BROMO-3-CHLOROPHENOL Chemical Properties

Melting point:

64-66°C

Boiling point:

267.5±20.0 °C(Predicted)

Density 

1.788±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

form 

powder to crystal

pka

8.43±0.18(Predicted)

color 

White to Almost white

Water Solubility 

Slightly soluble in water.

BRN 

3236445

InChI

InChI=1S/C6H4BrClO/c7-5-2-1-4(9)3-6(5)8/h1-3,9H

InChIKey

FQEYHIPPYOSPLF-UHFFFAOYSA-N

SMILES

C1(O)=CC=C(Br)C(Cl)=C1

CAS DataBase Reference

13631-21-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

36/37/38-22

Safety Statements 

26-36/37/39

WGK Germany 

WGK 3

HS Code 

2908.19.6000

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

MSDS

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4-BROMO-3-CHLOROPHENOL Usage And Synthesis

Uses

4-Bromo-3-chlorophenol is used as a precursor in organic synthesis to prepare 4-(benzyloxy)-l-bromo-2-chlorobenzene by reaction with benzyl bromide.

Synthesis

45.7 g (0.466 mol) of 3-chlorophenol and 80 mL of carbon tetrachloride were added into a four-necked flask, and 82.74 g (0.465 mol) of NBS was added in batches under stirring, and the reaction was carried out at a certain temperature temperature, and the samples were taken every 2 h, and analyzed by gas chromatography, and the reaction was stopped when the mass fraction of 3-chlorophenol was less than 1 %. Filtering, the filtrate was washed with water, the oil layer was taken for distillation, and the 37-38 ?? / 0.000 4 MPa fraction was collected as the 4-bromo-3-chlorophenol product, the purity of which was greater than 98% (GC), with a yield of 87%.

4-BROMO-3-CHLOROPHENOL(13631-21-5)Related Product Information

• 4-Bromo-2,6-dimethylaniline
• 4-Bromo-3-fluorobenzonitrile
• 4-Bromo-3-fluorobenzaldehyde
• 4-Bromo-2-chlorobenzonitrile
• 4-Bromo-3-methylphenol
• 4-BROMO-2-METHYLANISOLE
• 4-Bromo-3-fluorobenzoic acid
• 4-Bromo-2-fluorobenzotrifluoride
• 4-Bromo-2-methyl-benzaldehyde
• 4-Bromo-2-fluoroanisole
• 4-Bromo-2-methylpyridine
• 4-BROMO-3-CHLOROPHENOL
• BROMOPHOS-ETHYL
• 4-Bromo-2,5-dichlorophenol
• 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis[2-bromo-6-chlorophenol] S,S-dioxide,4,4'-[(3H-2,1-Benzoxathiole 2,2-dioxide)-3-ylidene]bis(2-bromo-6-chlorophenol)
• 2,2’-methylenebis(6-bromo-4-chlorophenol
• 3-Bromo-2-chlorophenol
• LEPTOPHOS