CHLOROMETHYL METHYL SULFIDE Chemical Properties

Boiling point:

105 °C (lit.)

Density 

1.153 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.498(lit.)

Flash point:

63 °F

storage temp. 

2-8°C

form 

clear liquid

color 

Colorless to Light orange to Yellow

Water Solubility 

Soluble in acetonitrile, ether and dichloromethane. Insoluble in water.

Sensitive 

Moisture Sensitive

BRN 

1730851

CAS DataBase Reference

2373-51-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

F,Xi

Risk Statements 

11-37

Safety Statements 

9-16-33

RIDADR 

UN 1993 3/PG 2

WGK Germany 

3

RTECS 

WQ3700000

F 

13

HazardClass 

3

PackingGroup 

II

HS Code 

2930909899

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

CHLOROMETHYL METHYL SULFIDE Usage And Synthesis

Chemical Properties

CLEAR YELLOW TO BROWN LIQUID

Uses

Chloromethyl methyl sulfide is used as a methylene transfer reagent for iron(II) mediated cyclopropanation and for carbonyl and aromatic compounds. It protects alcohols as their methylthiomethyl (MTM) ethers by reaction, e.g. with NaH/NaI in DME. It is also used for the preparation of MTM esters of carboxylic acids, e.g. by treatment of the K salt of the acid in the presence of NaI and 18-crown-6 and for reaction with cyclopentadienyl iron dicarbonyl dimer in the formation of an iron-containing methylene transfer agent.

Uses

Methylthiomethylating reagent for carbonyl and aromatic compounds. Methylene transfer reagent for iron(II) mediated cyclopropanation.

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 6127, 1994 DOI: 10.1016/0040-4039(94)88094-8

CHLOROMETHYL METHYL SULFIDE(2373-51-5)Related Product Information

• Stannous chloride dihydrate
• CHLOROMETHYL PHENYL SULFIDE
• CHLOROMETHYL METHYL SULFIDE
• CHLOROMETHYL PHENYL SULFONE
• bis(trichloromethyl) sulphone
• PHENYL CHLOROTHIOFORMATE
• CHLOROMETHYL 4-CHLOROPHENYL SULFIDE
• CHLOROMETHYL PHENYL SULFOXIDE
• Ethyl chlorothioformate
• CHLOROMETHYL THIOCYANATE
• 2-chloromethyl methyl sulfide
• CHLOROMETHYL TRIFLUOROMETHYL SULFIDE
• P-TOLUENESULFONYLMETHYL CHLORIDE
• N-PROPYL CHLOROTHIOFORMATE
• 1-chloro-4-[(chloromethyl)sulphonyl]benzene
• BIS(CHLOROMETHYL) SULFIDE
• PHENYL CHLORODITHIOFORMATE
• P-CHLOROPHENYL TRICHLOROMETHYL SULFIDE