Basic information Applications Appearance Solubility Applications Notes Safety Supplier Related
ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Spectral Standards >  4-Aminoacetophenone

4-Aminoacetophenone

Basic information Applications Appearance Solubility Applications Notes Safety Supplier Related

4-Aminoacetophenone Basic information

Product Name:
4-Aminoacetophenone
Synonyms:
  • 1-(4-aminophenyl)-ethanon
  • 1-(4-aminophenyl)ethanone[qr]
  • 4’-amino-acetophenon
  • 4’-aminoacetophenone[qr]
  • Acetophenone, p-amino-
  • Acetophenone,4’-amino-
  • acetophenone,4-amino-[qr]
  • acetophenone,p-amino-[qr]
CAS:
99-92-3
MF:
C8H9NO
MW:
135.16
EINECS:
202-801-2
Product Categories:
  • Amines
  • Aromatics
Mol File:
99-92-3.mol
More
Less

4-Aminoacetophenone Chemical Properties

Melting point:
103-107 °C(lit.)
Boiling point:
293 °C(lit.)
Density 
0,77 g/cm
refractive index 
1.5700 (estimate)
Flash point:
292-294°C
storage temp. 
Refrigerator
solubility 
6.5g/l
pka
2.17±0.10(Predicted)
form 
Crystalline Powder
color 
Slightly yellow to brown
Specific Gravity
0.77
Water Solubility 
It is soluble in hot water, ethanol and ether.
Merck 
14,413
BRN 
471493
InChIKey
GPRYKVSEZCQIHD-UHFFFAOYSA-N
CAS DataBase Reference
99-92-3(CAS DataBase Reference)
NIST Chemistry Reference
Acetophenone, 4'-amino-(99-92-3)
EPA Substance Registry System
4'-Aminoacetophenone (99-92-3)
More
Less

Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
26-36
WGK Germany 
3
RTECS 
AM5500000
TSCA 
T
HazardClass 
IRRITANT-HARMFUL
HS Code 
29223900
Hazardous Substances Data
99-92-3(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 381 mg/kg

MSDS

More
Less

4-Aminoacetophenone Usage And Synthesis

Applications

A novel utilization of aminophenone derivative in toxicology, for treating intoxications with cyanogenic toxic substances.

Appearance

Light Yellow to Tan Solid

Solubility

It is soluble in hot water, ethanol and ether.

Applications

4′-Aminoacetophenone, is used in pharmaceuticals, medicines and other organic products. It is also used as a reagent for the photometric determination of Ce. As pharmaceutical intemediate or in the determination of palladium and vitaminB1.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. acids, Incompatible to Acid chlorides, Acid anhydrides, Chloroformates, Strong oxidizing agents, Strong reducing agents. Stable under ordinary conditions.

Chemical Properties

SLIGHTLY YELLOW TO BROWN CRYSTALLINE POWDER

Uses

A novel utilization of aminophenone derivative in toxicology, for treating intoxications with cyanogenic toxic substances.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 34, p. 2013, 1986 DOI: 10.1248/cpb.34.2013
Tetrahedron Letters, 27, p. 4687, 1986 DOI: 10.1016/S0040-4039(00)85038-8

Safety Profile

Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NO,. See also AROMATIC AMINES

Purification Methods

It is soluble in hot H2O. UV (EtOH) has max 403nm (log 4.42) [Johnson J Am Chem Soc 75 2720 1953]. [Vandenbelt Anal Chem 26 726 1954.] The 2,4-dinitrophenylhydrazone has m 266-267o (from CHCl3 or EtOH) with 403nm (log 4.42), and the max semicarbazone has m 193-194o(dec)(from MeOH). The hydrochloride has m 98o(dec)(from H2O). [Beilstein 14 IV 100.]

4-AminoacetophenoneSupplier

Changzhou Xianlin Pharmaceutical Co., Ltd. Gold
Email
xlswyy@126.com
Taizhou FRIEND Chemical Co., Ltd. Gold
Tel
0523-86200082
Email
msw05428220@163.com
Nanjing Duolong Bio-tech Co.,Ltd. Gold
Email
sales@dolonchem.com
Hebei Minshang Biotechnology Co., Ltd Gold
Email
monica@hbminshang.com
Hebei Fen Xiang Trading Co.,Ltd Gold
Email
lisa@fenxiangtrade.com