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Lefamulin

Basic information Safety Supplier Related

Lefamulin Basic information

Product Name:
Lefamulin
Synonyms:
  • Lefamulin
  • 2-[[(1R,2R,4R)-4-Amino-2-hydroxycyclohexyl]thio]acetic acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
  • BC 3781
  • Lefamulin(BC-3781)
  • Acetic acid, 2-[[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
  • (3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,2R,4R)-4-amino-2-hydroxycyclohexyl)thio)acetate
CAS:
1061337-51-6
MF:
C28H45NO5S
MW:
507.73
Product Categories:
  • API
Mol File:
1061337-51-6.mol
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Lefamulin Chemical Properties

Boiling point:
618.6±55.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
solubility 
DMF: 16 mg/mL; DMSO: 12 mg/mL; Ethanol: 3 mg/mL; PBS (pH 7.2): 0.25 mg/mL
form 
A solid
pka
14.45±0.60(Predicted)
color 
White to off-white
InChIKey
KPVIXBKIJXZQJX-FCEONZPQSA-N
SMILES
C(O[C@@H]1C[C@](C=C)(C)[C@@H](O)[C@H](C)[C@@]23CC[C@@H](C)[C@]1(C)[C@]2([H])C(=O)CC3)(=O)CS[C@@H]1CC[C@@H](N)C[C@H]1O
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Lefamulin Usage And Synthesis

Uses

Lefamulin is an antibiotic medication used in the treatment of adults with community-acquired bacterial pneumonia.

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