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Z-Gly-Gly-Arg-AMC (acetate)

Basic information Safety Supplier Related

Z-Gly-Gly-Arg-AMC (acetate) Basic information

Product Name:
Z-Gly-Gly-Arg-AMC (acetate)
Synonyms:
  • CS-2037
  • Z-Gly-Gly-Arg-AMC (acetate)
  • Z-Gly-Gly-Arg-AMC acetate,Z-GGRAMC acetate
  • Benzyl (S)-(2-((2-((5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-2-oxoethyl)amino)-2-oxoethyl)carbamate acetate
CAS:
2070009-61-7
MF:
C30H37N7O9
MW:
639.67
Mol File:
2070009-61-7.mol
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Z-Gly-Gly-Arg-AMC (acetate) Chemical Properties

form 
Solid
color 
White to off-white
Sequence
Z-Gly-Gly-Arg-AMC
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Z-Gly-Gly-Arg-AMC (acetate) Usage And Synthesis

Uses

Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

References

[1] Tarandovskiy ID, et al. Antiplatelet agents can promote two-peaked thrombin generation in platelet rich plasma: mechanism and possible applications. PLoS One. 2013;8(2):e55688. DOI:10.1371/journal.pone.0055688
[2] Machlus KR, et al. Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram. Thromb Haemost. 2009 Nov;102(5):936-44. DOI:10.1160/TH09-03-0180

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