6-Bromo-5-methoxypicolinic acid Chemical Properties

Boiling point:

362.8±42.0 °C(Predicted)

Density 

1.713±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

3.52±0.10(Predicted)

InChI

InChI=1S/C7H6BrNO3/c1-12-5-3-2-4(7(10)11)9-6(5)8/h2-3H,1H3,(H,10,11)

InChIKey

WOXIJGVDMQJTAC-UHFFFAOYSA-N

SMILES

C1(C(O)=O)=NC(Br)=C(OC)C=C1

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-37/39

HS Code 

29339900

6-Bromo-5-methoxypicolinic acid Usage And Synthesis

Chemical Properties

White solid

Synthesis

2-Bromo-3-methoxy-6-methylpyridine 760 mg (3.76 mmol) was dissolved in 15 ml of water, and to the resulting solution was added potassium permanganate (KMnO4) (1.49 g, 9.40mmol) and the mixture was heated at 80 °C for 3 hrs. After TLC was conducted, pH was adjusted to 4 with 10 percent hydrochloric acid (HCl) and filtration was conducted with celite. The filtrate was extracted with 50 ml of ethyl acetate (EA). The organic layer was treated with magnesium sulfate (MgSO4) and filtered, and the solution was concentrated to give 6-Bromo-5-methoxypicolinic acid as a white solid (665 mg, 2.87 mmol, 75 percent) without purification.

6-Bromo-5-methoxypicolinic acid(54232-43-8)Related Product Information

• 5-METHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
• 5-Methoxyisoindoline hydrochloride
• 5-METHOXY-2,3-DIHYDRO-ISOINDOL-1-ONE
• 5-Methoxybenzofuran-2-carboxylic acid
• 3-Methoxy-6-Amino-2-Picoline
• 5-Methoxybenzofuran
• Ethyl 5-methoxypyrazine-2-carboxylate
• 6-Bromo-5-methoxypicolinic acid
• 5-METHOXYPYRIDINE-2-CARBOXYLIC ACID
• 2-BROMO-3-METHOXYPYRIDINE
• 5-BROMO-2-METHOXY-3-PYRIDINECARBOXYLIC ACID
• 2-BROMO-6-METHOXY-4-PYRIDINECARBOXYLIC ACID
• methyl 6-bromo-5-[(3-methylbenzyl)oxy]-2-pyridinecarboxylate
• 6-BROMO-5-ETHOXY-2-PYRIDINECARBOXYLIC ACID
• methyl 6-bromo-5-methoxy-2-pyridinecarboxylate
• 6-bromo-5-[(3-methylbenzyl)oxy]-2-pyridinecarboxylic acid
• methyl 5-(allyloxy)-6-bromo-2-pyridinecarboxylate
• 5-(allyloxy)-6-bromo-2-pyridinecarboxylic acid