Propargyl-PEG5-alcohol CAS#: 1036204-60-0

Propargyl-PEG5-alcohol Basic information

Product Name:

Propargyl-PEG5-alcohol

Synonyms:

Propargyl-PEG6-alcohol
HC≡C-CH2-PEG5-OH
Alkyne-PEG5-OH
Propargyl-PEG6-alcohol, Propargyl-PEG6-0H
3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol
Propargyl-P5
Propargyl-PEG5-OH/3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol
HO-PEG5-Propargyl

CAS:

1036204-60-0

MF:

C13H24O6

MW:

276.33

Product Categories:

peg

Mol File:

1036204-60-0.mol

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Propargyl-PEG5-alcohol Chemical Properties

Boiling point:: 368.1±37.0 °C(Predicted)
Density: 1.078±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
pka: 14.36±0.10(Predicted)
form: Liquid
color: Colorless to light yellow

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Propargyl-PEG5-alcohol Usage And Synthesis

Description

Propargyl-PEG6-alcohol is alkyne linker that can react with azide compounds via copper catalyzed azide-alkyne Click Chemistry. The hydrophilic PEG8 spacer increases solubility in aqueous environment.

Uses

Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] Robert Zamboni, et al. Raf-degrading conjugate compounds. WO2018200981A1.

Propargyl-PEG5-alcoholSupplier

Alabiochem Tech.Co., Ltd.

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Email: sales@alabiochem.com

T&W GROUP

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Sichuan Wei Keqi Biological Technology Co., Ltd.

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Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
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Borenpharm Co., Ltd

Tel: 027-65563561
Email: sales@borenpharm.com

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