DNP-PEG3-DNP Chemical Properties

Boiling point:

735.3±60.0 °C(Predicted)

Density 

1.478±0.06 g/cm3(Predicted)

pka

-4.96±0.50(Predicted)

DNP-PEG3-DNP Usage And Synthesis

Description

DNP-PEG3-DNP is a PEG linker containing two DNP moieties. DNP is involved in biological applications such as participating in ion transport across membranes. The hydrophilic PEG chain increases the solubility of the compound in aqueous media.

Uses

DNP-PEG3-DNP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DNP-PEG3-DNP(1365655-92-0)Related Product Information

• DNP-PEG5-NH2
• DNP-PEG2-OH
• DNP-PEG3-azide
• DNP-PEG4-acid
• DNP-PEG1-NH2