S-acetyl-PEG6-Tos Chemical Properties

Boiling point:

591.0±50.0 °C(Predicted)

Density 

1.202±0.06 g/cm3(Predicted)

S-acetyl-PEG6-Tos Usage And Synthesis

Biological Activity

S-acetyl-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

S-acetyl-PEG6-Tos(1818294-25-5)Related Product Information

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