Tos-PEG5 t-butyl ester CAS#: 581065-94-3

Tos-PEG5 t-butyl ester Basic information

Product Name:

Tos-PEG5 t-butyl ester

Synonyms:

tert-butyl 3-[2-(2-{2-[2-(toluene-4-sulfonyloxy)-ethoxy]ethoxy}ethoxy)ethoxy]propionate
CAS_581065-94-3
Tos-PEG5 t-butyl ester
tert-Butyl 1-(Tosyloxy)-3,6,9,12-tetraoxapentadecan-15-oate
Tos-PEG5-Boc
Tos-PEG5-COOtBu
4,7,10,13-Tetraoxapentadecanoic acid, 15-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
Tos-PEG4-COOtBu

CAS:

581065-94-3

MF:

C22H36O9S

MW:

476.58

Mol File:

581065-94-3.mol

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Tos-PEG5 t-butyl ester Chemical Properties

Boiling point:: 560.5±50.0 °C(Predicted)
Density: 1.151±0.06 g/cm3(Predicted)
refractive index: 1.49
form: clear liquid
color: Colorless to Light yellow

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Safety Information

HS Code: 2918.99.4700

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Tos-PEG5 t-butyl ester Usage And Synthesis

Description

Tos-PEG5-t-butyl ester is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Uses

This compound is used in preparation of taxanes. Taxanes have improved its toxicity and solubility in aqueous solution compared to paciitaxel.

Tos-PEG5 t-butyl esterSupplier

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