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Sacubitril Impurity

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Sacubitril Impurity Basic information

Product Name:
Sacubitril Impurity
Synonyms:
  • 1012341-48-8 enantioMer
  • (2E,4S)-5-[1,1-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic Acid
  • impurity 41
  • 2-Pentenoic acid, 5-[1,1'-biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-, (2E,4S)-
  • Sacubitril Impurity
  • (S,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid
  • Sacubitril Impurity 103
  • (2E,4S)-5-[1,1'-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic acid
CAS:
1015037-46-3
MF:
C23H27NO4
MW:
381.46
Mol File:
1015037-46-3.mol
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Sacubitril Impurity Chemical Properties

Boiling point:
595.6±50.0 °C(Predicted)
Density 
1.132±0.06 g/cm3(Predicted)
pka
4.67±0.19(Predicted)
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Sacubitril Impurity Usage And Synthesis

Uses

(2E,4S)-5-[1,1''-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic Acid was used in the study to process for preparation of biaryl-substituted 4-aminobutyric acids by hydrogenation of the corresponding alkenoates.

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