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Ezetimibe (RSS)-Isomer

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Ezetimibe (RSS)-Isomer Basic information

Product Name:
Ezetimibe (RSS)-Isomer
Synonyms:
  • (3S,4S)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
  • (3S,4S,3'R)-Ezetimibe
  • Ezetimibe (RSS)-Isomer
  • Ezetimibe impurities 6
  • Ezetimibe Impurity T
  • Ezetimibe-24
  • Ezetimibe impuriry 23/ Ezetimibe (3S,4S,3’R)-Isomer/(3S,4S)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
  • Ezetimibe (3S,4R,3'R)-Isomer
CAS:
1478664-18-4
MF:
C24H21F2NO3
MW:
409.43
Mol File:
1478664-18-4.mol
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Ezetimibe (RSS)-Isomer Chemical Properties

Boiling point:
654.9±55.0 °C(Predicted)
Density 
1.334±0.06 g/cm3(Predicted)
pka
9.72±0.30(Predicted)
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Ezetimibe (RSS)-Isomer Usage And Synthesis

Uses

(3S,4S,3''R)-Ezetimibe is derived from (3S,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone (F595055), which is an intermediate in the synthesis of (3S,4S,3’S)-Ezetimbe (E975040), which is a 3-epimer impurity of Ezetimibe (E975000), a cholesterol absorption inhibitor.

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