Siremadlin
Siremadlin Basic information
- Product Name:
- Siremadlin
- Synonyms:
-
- (6S)-5-(5-chloro-1,2-dihydro-1-methyl-2-oxo-3-pyridinyl)-6-(4-chlorophenyl)-2-(2,4-dimethoxy-5-pyrimidinyl)-5,6-dihydro-1-(1-methylethyl)-Pyrrolo[3,4-d]imidazol-4(1H)-one
- HDM-201
- NVP-HDM201
- CS-2613
- CS-2787
- HDM201; HDM 201; HDM-201; NVP-HDM201; NVP-HDM-201; NVP-HDM 201
- (S)-5-(5-chloro-1-methyl-2-oxo-1,2-dihydropyridin-3-yl)-6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-1-isopropyl-5,6-dihydropyrrolo[3,4-d]imidazol-4(1H)-one
- Siremadlin
- CAS:
- 1448867-41-1
- MF:
- C26H24Cl2N6O4
- MW:
- 555.41
- Mol File:
- 1448867-41-1.mol
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Siremadlin Chemical Properties
- Boiling point:
- 736.5±70.0 °C(Predicted)
- Density
- 1.47±0.1 g/cm3(Predicted)
- pka
- 1.33±0.29(Predicted)
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Siremadlin Usage And Synthesis
Uses
Siremadlin is an oral biologic agent that is a selective inhibitor of the p53-MDM2 interaction and is being investigated for the treatment of patients with myeloid malignancies after showing single agent activity in preclinical studies. the safety profile of Siremadlin did not differ significantly between tumor types and treatment regimens.
SiremadlinSupplier
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
BOC Sciences
- Tel
- 16314854226
- info@bocsci.com
Dtchem Laboratories,（Gan Su）Co.,Ltd.
- Tel
- 18993966060
- sales@techbiochem.com
ShangHai Caerulum Pharma Discovery Co., Ltd.
- Tel
- 021-64556180 15000803246
- sales-cpd@caerulumpharma.com
Shanghai YuanQi Biotechnology Co., Ltd.
- Tel
- +86-2332782371 +86-18120098618
- sales@adobechem.com