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N-Benzyloctadecenamide

Basic information Safety Supplier Related

N-Benzyloctadecenamide Basic information

Product Name:
N-Benzyloctadecenamide
Synonyms:
  • (9Z)-N-(Phenylmethyl)-9-octadecenamide
  • N-Benzyloctadecenamide
  • 9-Octadecenamide, N-(phenylmethyl)-, (9Z)-
  • (9Z)-N-Benzyl-9-octadecenamide
CAS:
101762-87-2
MF:
C25H41NO
MW:
371.6
Mol File:
101762-87-2.mol
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N-Benzyloctadecenamide Chemical Properties

Melting point:
58-59 °C
Boiling point:
534.2±39.0 °C(Predicted)
Density 
0.923±0.06 g/cm3(Predicted)
pka
16.39±0.46(Predicted)
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N-Benzyloctadecenamide Usage And Synthesis

Description

N-Benzyloleamide is a natural compound found in a variety of plants such as Tropaeolum tuberosum tubers and Lepidium meyenii (Maca). N-Benzyloleamide has been shown to have anti-inflammatory activity with IC50 values of 6.50±0.75 μM, 7.74±0.19 μM, and 8.37±0.09 μM in CCD-1109Sk, MRC-5, and RWPE-1 cell lines, respectively[1].  In addition, it has been shown to have a concentration-dependent inhibitory effect on fatty acid amide hydrolase (FAAH), an enzyme responsible for the degradation of endogenous cannabinoids in the nervous system[2].

References

[1] TICONA L A, COBALLES M R, POTENTE G, et al. Anti-inflammatory Potential of Macamides Isolated from Yellow Tubers of Mashua (Tropaeolum Tuberosum)[J]. Planta Medica International Open, 2020. DOI:10.1055/a-1159-4242.
[2] M ALASMARI. Inhibition of Fatty Acid Amide Hydrolase (FAAH) by Macamides.[J]. Molecular Neurobiology, 2019. DOI:10.1007/s12035-018-1115-8.

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