N-Benzyloctadecenamide
N-Benzyloctadecenamide Basic information
- Product Name:
- N-Benzyloctadecenamide
- Synonyms:
-
- (9Z)-N-(Phenylmethyl)-9-octadecenamide
- N-Benzyloctadecenamide
- 9-Octadecenamide, N-(phenylmethyl)-, (9Z)-
- (9Z)-N-Benzyl-9-octadecenamide
- CAS:
- 101762-87-2
- MF:
- C25H41NO
- MW:
- 371.6
- Mol File:
- 101762-87-2.mol
N-Benzyloctadecenamide Chemical Properties
- Melting point:
- 58-59 °C
- Boiling point:
- 534.2±39.0 °C(Predicted)
- Density
- 0.923±0.06 g/cm3(Predicted)
- pka
- 16.39±0.46(Predicted)
N-Benzyloctadecenamide Usage And Synthesis
Description
N-Benzyloleamide is a natural compound found in a variety of plants such as Tropaeolum tuberosum tubers and Lepidium meyenii (Maca). N-Benzyloleamide has been shown to have anti-inflammatory activity with IC50 values of 6.50±0.75 μM, 7.74±0.19 μM, and 8.37±0.09 μM in CCD-1109Sk, MRC-5, and RWPE-1 cell lines, respectively[1]. In addition, it has been shown to have a concentration-dependent inhibitory effect on fatty acid amide hydrolase (FAAH), an enzyme responsible for the degradation of endogenous cannabinoids in the nervous system[2].
References
[1] TICONA L A, COBALLES M R, POTENTE G, et al. Anti-inflammatory Potential of Macamides Isolated from Yellow Tubers of Mashua (Tropaeolum Tuberosum)[J]. Planta Medica International Open, 2020. DOI:10.1055/a-1159-4242.
[2] M ALASMARI. Inhibition of Fatty Acid Amide Hydrolase (FAAH) by Macamides.[J]. Molecular Neurobiology, 2019. DOI:10.1007/s12035-018-1115-8.
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