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7-(Difluoromethyl)Quinoline

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7-(Difluoromethyl)Quinoline Basic information

Product Name:
7-(Difluoromethyl)Quinoline
Synonyms:
  • 7-(Difluoromethyl)Quinoline
  • 7-(Difluoromethyl)Quinoline(WXC01613)
  • Quinoline, 7-(difluoromethyl)-
CAS:
1261728-71-5
MF:
C10H7F2N
MW:
179.17
Mol File:
1261728-71-5.mol
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7-(Difluoromethyl)Quinoline Usage And Synthesis

Uses

7-(Difluoromethyl)quinoline is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.

Application

7-(Difluoromethyl)Quinoline can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

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