Defensin HNP-1 (human)
Defensin HNP-1 (human) Basic information
- Product Name:
- Defensin HNP-1 (human)
- Synonyms:
-
- Human Defensin NP-1
- L-Cysteine, L-alanyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginyl-L-isoleucyl-L-prolyl-L-alanyl-L-cysteinyl-L-isoleucyl-L-alanylglycyl-L-α-glutamyl-L-arginyl-L-arginyl-L-tyrosylglycyl-L-threonyl-L-cysteinyl-L-isoleucyl-L-tyrosyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-tryptophyl-L-alanyl-L-phenylalan...
- CAS:
- 148093-65-6
- MF:
- C150H222N44O38S6
- MW:
- 3442.02968
- Mol File:
- 148093-65-6.mol
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Defensin HNP-1 (human) Chemical Properties
- Density
- 1.53±0.1 g/cm3(Predicted)
- Sequence
- H-Ala-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys-OH (Disulfide bonds between Cys2 and Cys3?/Cys? and Cys1?/Cys? and Cys2?)
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Defensin HNP-1 (human) Usage And Synthesis
Uses
Defensin HNP-1 human is a Human neutrophil peptides (HNPs), involved in endothelial cell dysfunction at the time of early atherosclerotic development. Defensin HNP-1 human exhibits broad antimicrobial and anti-leishmanial activities[1][2].
IC 50
Leishmania
References
[1] Dabirian S, et, al. Human neutrophil peptide-1 (HNP-1): a new anti-leishmanial drug candidate. PLoS Negl Trop Dis. 2013 Oct 17;7(10):e2491. DOI:10.1371/journal.pntd.0002491
[2] Higazi M, et, al. Opposing effects of HNP1 (α-defensin-1) on plasma cholesterol and atherogenesis. PLoS One. 2020 Apr 17;15(4):e0231582. DOI:10.1371/journal.pone.0231582
Defensin HNP-1 (human)Supplier
Nanjing Leon Biological Technology Co., Ltd.
- Tel
- 17705183659
- sales@njleonbiotech.com
Nanjing Peptide Biotech Ltd.
- Tel
- 025-58361106-805 15951641583
- zhao.xu@njpeptide.com
Chengdu Youngshe Chemical Co., Ltd.
- Tel
- +86-17380623303
- Caroline@youngshechem.com
Hangzhou Peptidego Biotech Co.,Ltd.
- Tel
- 0571-87213919
- Eric@peptidego.com
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
- Tel
- meitaochem@126.com
- meitaochem@126.com