3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionic acid Chemical Properties

Melting point:

172-174°C

Boiling point:

364.3±37.0 °C(Predicted)

Density 

1.049±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)

form 

Solid

pka

4.79±0.10(Predicted)

color 

White to Off-White

Water Solubility 

Slightly soluble in water.

CAS DataBase Reference

20170-32-5(CAS DataBase Reference)

EPA Substance Registry System

3,5-Di-tert-butyl-4-hydroxyhydocinnamic acid (20170-32-5)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

2918290090

MSDS

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3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionic acid Usage And Synthesis

Application

One important application of 3-(3, 5-tert-butyl-4-hydroxyphenyl) propionic acid is in the synthesis of antioxidant. Most widespread stabilizers of phenolic structure are derivatives of a methyl ester 3-(3’,5’-di-tert.buyil-4’-hylroxyphenyl)-propionic acid, productions which are based on ester exchanges polyatomic alcohols. To the most significant is pentaeritril-tetrakis-3-(3’,5’-di-tert.buyil-4’- hylroxyphenyl)-propionate.
From the beginning of works on synthesis of derivatives of a methyl ester 3-(3’,5’-di-tert.buyil-4’-hylroxyphenyl)- propionic acid on the present are executed a series of basic researches on catalysis and technology.
And in the present work 3-(3,5-di-tert-butyl-4-hydroxy-phenyl)-propionic acid can be used as antioxidant group to modify esters. This kind of esters is useful in many fields, such as lubricating oil and cutting compound, because of two important functions (antioxidant and lubricant) in the same compound.

Safely

The toxicity of 3-(3,5-di-tert-butyl-4- hydroxyphenyl)propanoic acid, esters with C13-C15 branched and linear alcohols has been tested by EFSA. And this scientific opinion of EFSA deals with the risk assessment of the additive, 3-(3,5-di-tert-butyl-4- hydroxyphenyl)propanoic acid, esters with C13-C15 branched and linear alcohols, CAS No. 171090- 93-0, REF. No. 47060 for which the CEF Panel concluded that there is no safety concern for the consumer if the substance is used only in polyolefins in contact with foods other than fatty/highalcoholic and dairy products and its migration does not exceed 0.05 mg/kg food.

Uses

It is employed as an active pharmaceutical intermediate.

3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionic acid(20170-32-5)Related Product Information

• Di-tert-butyl peroxide
• (S)-(+)-2-Phenylpropionic acid
• Buprofezin
• Propionic acid
• BUTYL OLEATE
• Dibutyl phthalate
• L(+)-Lactic acid
• Butylated hydroxyanisole
• Diethylene glycol monobutyl ether
• Butylated Hydroxytoluene
• Butyl acetate
• Cyhalofop-butyl
• Zoledronic Acid Impurity 20
• L-Methionine, S-oxide, [S(S)]-
• (R)-4-(3-((tert-butoxycarbonyl)amino)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate
• Zolpidem-d6 Phenyl-4-carboxylic Acid
• Zolpidem-d6 6-Carboxylic Acid
• Hexamethylene bis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate]