Basic information Safety Supplier Related

PEG8-Tos

Basic information Safety Supplier Related

PEG8-Tos Basic information

Product Name:
PEG8-Tos
Synonyms:
  • PEG8-Tos
  • Tos-PEG7-OH
  • 3,6,9,12,15,18-Hexaoxaeicosane-1,20-diol, 1-(4-methylbenzenesulfonate)
  • OH-PEG7-Tos
  • HO-(CH2CH2O)7-Tos
  • Tos-PEG7-OH/ 3,6,9,12,15,18-Hexaoxaeicosane-1,20-diol, 1-(4-methylbenzenesulfonate)
  • PEG8-Tosylate
  • Tos-PEG7-alcohol
CAS:
1028089-05-5
MF:
C21H36O10S
MW:
480.57
Mol File:
1028089-05-5.mol
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PEG8-Tos Chemical Properties

storage temp. 
Store at 0-8 °C
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PEG8-Tos Usage And Synthesis

Description

PEG8-Tos is a PEG linker containing a hydroxyl group with a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Uses

Tos-PEG7-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6

PEG8-TosSupplier

Nanjing Junnahe Biopharmaceutical Co., Ltd
Tel
025-58367986 17351780683
Email
amy.xiang@ally-chem.com
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Email
product02@bidepharm.com
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Email
3003855609@qq.com
Jinan elephant international trading co., LTD
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Email
13006575422@163.com
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Email
info@amateksci.com
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PEG8-Tos(1028089-05-5)Related Product Information