(-)-TRAMADOL, HYDROCHLORIDE Chemical Properties

Melting point:

171-172°C

storage temp. 

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

solubility 

Chloroform (Slightly), Methanol (Sparingly), Water (Slightly)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

(-)-TRAMADOL, HYDROCHLORIDE Usage And Synthesis

Chemical Properties

White Solid

Uses

(-)-Tramadol Hydrochloride is an analgesic. Used in the treatment of urinary incontinence

Definition

ChEBI: (S,S)-tramadol hydrochloride is a hydrochloride resulting from the reaction of (S,S)-tramadol with 1 molar equivalent of hydrogen chloride; the (S,S)-enantiomer of the racemic opioid analgesic tramadol hydrochloride, it exhibits ten-fold lower analgesic potency than the (R,R)-enantiomer. It has a role as a delta-opioid receptor agonist, a kappa-opioid receptor agonist, a mu-opioid receptor agonist, an adrenergic uptake inhibitor, an antitussive, a capsaicin receptor antagonist, a muscarinic antagonist, a NMDA receptor antagonist, an opioid analgesic, a serotonergic antagonist and a serotonin uptake inhibitor. It contains a (S,S)-tramadol(1+). It is an enantiomer of a (R,R)-tramadol hydrochloride.

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