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Alkyne NHS ester (hexynoic acid NHS ester)

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Alkyne NHS ester (hexynoic acid NHS ester) Basic information

Product Name:
Alkyne NHS ester (hexynoic acid NHS ester)
Synonyms:
  • Alkyne NHS ester (hexynoic acid NHS ester)
  • 2,5-dioxopyrrolidin-1-yl hex-5-ynoate
  • Propargyl-C2-NHS ester
  • 5-Hexynoic acid NHS ester
  • 5-Hexynoic NHS ester
  • 5-Hexynoic acid 2,5-dioxo-1-pyrrolidinyl ester
  • hex-5-ynoic acid 2,5-dioxo-pyrrolidin-1-yl ester
  • N-succinimidyl 5-hexynoate
CAS:
906564-59-8
MF:
C10H11NO4
MW:
209.2
Mol File:
906564-59-8.mol
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Alkyne NHS ester (hexynoic acid NHS ester) Usage And Synthesis

Description

5-Hexynoic Acid-NHS Ester contains a propargyl group and an NHS ester group. This reagent is an amine reactive reagent for derivatizing peptides, antibodies, amine coated surfaces etc. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Uses

5-Hexynoic NHS Ester is a nonclaevable linker for antibody-drug-conjugation. 5-Hexynoic NHS Ester is used in the preparation of biomimetic G-quartet compounds for detection, imaging and purification of G-quartet nucleic acids.

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