t-Boc-N-Amido-PEG6-Propargyl
t-Boc-N-Amido-PEG6-Propargyl Basic information
- Product Name:
- t-Boc-N-Amido-PEG6-Propargyl
- Synonyms:
-
- t-Boc-N-Amido-PEG6-Propargyl
- Propargyl-PEG6-NHBoc
- Boc-NH-PEG6-propargyl
- 5,8,11,14,17,20-Hexaoxa-2-azatricos-22-ynoic acid, 1,1-dimethylethyl ester
- Propargyl-PEG7-Boc Amine
- Propargyl-PEG6-NHBoc/5,8,11,14,17,20-Hexaoxa-2-azatricos-22-ynoic acid, 1,1-dimethylethyl ester
- T-Boc-N-amino-PEG6-propargyl
- CAS:
- 1262991-52-5
- MF:
- C20H37NO8
- MW:
- 419.51
- Mol File:
- 1262991-52-5.mol
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t-Boc-N-Amido-PEG6-Propargyl Chemical Properties
- solubility
- Soluble in DMSO, DCM, DMF
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t-Boc-N-Amido-PEG6-Propargyl Usage And Synthesis
Description
t-Boc-N-Amido-PEG6-propargyl can be used in copper catalyzed Click Chemistry reactions with azides. The Boc group can be removed under mild acidic conditions to yield the free amine.
Uses
Boc-NH-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG6-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-N-Amido-PEG6-PropargylSupplier
Borenpharm Co., Ltd
- Tel
- 027-65563561
- sales@borenpharm.com
Jinan elephant international trading co., LTD
- Tel
- 13006575422@163.com
Amatek Scientific Co. Ltd.
- Tel
- 0512-56316828
- info@amateksci.com
Aikon International Limited
- Tel
- 025-66061636 18013972705
- qqyang@aikonchem.com
SHANGHAI FDC-CHEMICAL CO.,LTD
- Tel
- 021-61469567 13482353728
- sales@fdc-chemical.com
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t-Boc-N-Amido-PEG6-Propargyl(1262991-52-5)Related Product Information
- t-Boc-N-Amido-PEG4-propargyl
- 2,2-DIMETHYL-4-OXO-3,8,11,14-TETRAOXA-5-AZAHEXADECAN-16-OIC ACID
- Boc-NH-PEG7-CH2CH2COOH
- 22-Amino-5,8,11,14,17,20-hexaoxa-2-azadocosanoic acid 1,1-dimethylethyl ester
- t-boc-N-amido-PEG5-azide
- t-Boc-N-amido-PEG5-acid
- Thiol-dPEG4-t-boc-N-amido
- t-Boc-N-amido-PEG4-(CH2)3CO2H
- t-Boc-N-amido-PEG5-MS
- t-Boc-N-amido-PEG5-NHS ester
- t-Boc-N-Amido-PEG7-propargyl
- t-Boc-N-Amido-PEG3-propargyl
- t-Boc-N-Amido-PEG4-Ms
- Boc-N-amido-PEG3-sulfonic acid
- t-Boc-N-Amido-PEG5-propargyl
- 5,8,11-Trioxa-2-azatridecanoic acid, 13-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
- t-Boc-N-Amido-PEG8-propargyl