Basic information Safety Supplier Related

4-AMINOTHIOBENZAMIDE

Basic information Safety Supplier Related

4-AMINOTHIOBENZAMIDE Basic information

Product Name:
4-AMINOTHIOBENZAMIDE
Synonyms:
  • 4-amino-benzenecarbothioamid
  • 4-aminobenzenecarbothioamide
  • p-aminobenzothiamide
  • p-aminothio-benzamid
  • 4-AMINOTHIOBENZAMIDE
  • 4-Amino Thiobenzamide p-Amino Thiobenzamide
  • PARA-AMINOTHIOBENZAMIDE
  • p-AminoThioBenzamide
CAS:
4714-67-4
MF:
C7H8N2S
MW:
152.22
Product Categories:
  • Amines
Mol File:
4714-67-4.mol
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4-AMINOTHIOBENZAMIDE Chemical Properties

Melting point:
185-190 °C
Boiling point:
325.6±44.0 °C(Predicted)
Density 
1.286
solubility 
DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 0.15 mg/ml
form 
A crystalline solid
pka
13.25±0.29(Predicted)
color 
Light yellow to yellow
CAS DataBase Reference
4714-67-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-43-36-22
Safety Statements 
26-36/37/39
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
2930909899
Toxicity
mouse,LD50,intraperitoneal,75mg/kg (75mg/kg),National Technical Information Service. Vol. AD691-490,
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4-AMINOTHIOBENZAMIDE Usage And Synthesis

Description

4-amino Benzthioamide is a synthetic intermediate useful for pharmaceutical synthesis.

Uses

3-Aminobenzothioamide is a small H2S donor. 3-Aminobenzothioamide has the potential for the research of myocardial ischemia-reperfusion injury[1][2].

References

[1] Sarkar S, et al. Hydrogels for Gasotransmitter Delivery: Nitric Oxide, Carbon Monoxide, and Hydrogen Sulfide. Macromol Biosci. 2024 Jan;24(1):e2300138. DOI:10.1002/mabi.202300138
[2] Zhang Q, et al. Hydrogen sulfide releasing hydrogel for alleviating cardiac inflammation and protecting against myocardiZhang Q, et al. Hydrogen sulfide releasing hydrogel for alleviating cardiac inflammation and protecting against myocardial ischemia-reperfusion injury. J Mater Chem B. 2022 Jul 20;10(28):5344-5351.al ischemia-reperfusion injury. J Mater Chem B. 2022 Jul 20;10(28):5344-5351. DOI:10.1039/d2tb00971d

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