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Bilastine N-Oxide

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Bilastine N-Oxide Basic information

Product Name:
Bilastine N-Oxide
Synonyms:
  • Bilastine N-Oxide
  • Bilastine Impurity 6
  • 1-(4-(2-carboxypropan-2-yl)phenethyl)-4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidine 1-oxide
  • Bilastine N-oxide Impurity
  • Benzeneacetic acid, 4-[2-[4-[1-(2-ethoxyethyl)-1H-benzimidazol-2-yl]-1-oxido-1-piperidinyl]ethyl]-α,α-dimethyl-
  • Bilastine Related compound A
  • 1-[4-(2-Carboxy-2-propyl)phenethyl]-4-[1-(2-ethoxyethyl)-2-benzimidazolyl]piperidine 1-Oxide
  • Bilastine N-Oxide (Mixture of cis and trans Isomers)
CAS:
2069238-47-5
MF:
C28H37N3O4
MW:
479.62
Mol File:
2069238-47-5.mol
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Bilastine N-Oxide Chemical Properties

Melting point:
139-159°C (dec.)
storage temp. 
-20°C, Inert atmosphere
solubility 
DMF (Slightly), DMSO (Slightly)
form 
Solid
pka
4.40±0.10(Predicted)
color 
White to Off-White
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Bilastine N-Oxide Usage And Synthesis

Uses

Bilastine N-Oxide is an impurity of Bilastine (B385000), which is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.

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