N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide Chemical Properties

Melting point:

151-152 °C

Boiling point:

436.4±45.0 °C(Predicted)

Density 

1.42±0.1 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

12.08±0.70(Predicted)

color 

White to Off-White

CAS DataBase Reference

90357-51-0(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

HS Code 

29269090

N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide Usage And Synthesis

Uses

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.

N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide(90357-51-0)Related Product Information

• Phenylhydrazine
• Methacrylamide
• N,N'-Methylenebisacrylamide
• 2,2-Dibromo-2-cyanoacetamide
• PHENYL VALERATE
• Acrylamide
• 4-Amino-2-(trifluoromethyl)benzonitrile
• Bicalutamide
• Bicalutamide EP Impurity K
• Desfluoro Bicalutamide
• BICALUTAMIDE-D4
• N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide
• Deshydroxy Bicalutamide
• 3-(4-Fluobenzenesulfhydry)-2-hydroxyl-2-methylpropionic acid
• Bicalutamide EP Impurity F
• N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(2-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
• N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide
• 3-Fluoro-4-desfluoro BicalutaMide