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DL-Homocystine

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DL-Homocystine Basic information

Product Name:
DL-Homocystine
Synonyms:
  • Dl-Homocycine
  • rac-4,4'-Dithiobis[(R*)-2-aminobutanoic acid]
  • dl-homocystine crystalline
  • DL-4,4'-Dithiobis[2-aminobutyric acid]
  • HOMOCYSTINE, DL-(RG)
  • H-DL-Hcys-OH)2
  • 2-Amino-4-(3-amino-3-carboxy-propyldisulfanyl)-butyricacid
  • DL- high cystine
CAS:
870-93-9
MF:
C8H16N2O4S2
MW:
268.35
EINECS:
212-803-5
Product Categories:
  • Amino Acids
  • Amino Acids
Mol File:
870-93-9.mol
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DL-Homocystine Chemical Properties

Melting point:
≥300 °C
alpha 
[α]D20 0±0.5゜(c=2,1mol/l HCl)
Boiling point:
507.6±50.0 °C(Predicted)
Density 
1.4269 (rough estimate)
refractive index 
1.6300 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Aqueous Acid (Slightly). Aqueous Base (Slightly)
form 
powder to crystal
pka
1.90±0.10(Predicted)
color 
White to Light yellow
Water Solubility 
0.2g/L(25 ºC)
Merck 
14,4735
BRN 
1728581
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
870-93-9(CAS DataBase Reference)
EPA Substance Registry System
Butanoic acid, 4,4'-dithiobis[2-amino-, (2R,2'R)-rel- (870-93-9)
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Safety Information

WGK Germany 
3
HS Code 
2930.90.9250

MSDS

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DL-Homocystine Usage And Synthesis

Chemical Properties

white to slightly beige solid

Uses

DL-Homocystine is used in the synthesis of potential antitumor agents through inhibition of L-asparagine. There is growing clinical evidence that elevated homocysteine levels are associated with an increased risk of venous and arterial thrombosis.

Definition

ChEBI: Homocystine is an organic disulfide obtained by oxidative dimerisation of homocysteine. It has a role as a human metabolite. It is a tautomer of a homocystine zwitterion.

Purification Methods

dl-Homocystine crystallises in platelets from water with 1H2O and m 258-260o(dec), all operations should be carried out under N2. [Sudo J Chem Soc Jpn (Pure Chem Sect) 79 81, 86, 87 1958, Beilstein 4 IV 3199.]

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