PIPERACILLIN
PIPERACILLIN Basic information
- Product Name:
- PIPERACILLIN
- Synonyms:
-
- (2s,5r,6r)-6-[[(2r)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- Piperacillin (500 mg)
- Piperacillin (350 mg)
- Piperacillin hydrat
- Piperacillin CRS
- PIPERACILLIN USP/EP/BP
- Piperacillin (1541500)
- Piperacillin Hydrate
- CAS:
- 66258-76-2
- MF:
- C23H29N5O8S
- MW:
- 535.57
- EINECS:
- 811-368-4
- Mol File:
- 66258-76-2.mol
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PIPERACILLIN Chemical Properties
- solubility
- Slightly soluble in water, freely soluble in methanol, slightly soluble in ethyl acetate.
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PIPERACILLIN Usage And Synthesis
Chemical Properties
White or almost white powder.
Uses
Penicillin antibacterial.
in vivo
Piperacillin (100 mg/kg, i.v., 4 times a day, 5 d) hydrate in combination with Tazobactam (HY-B1418)(12.5 mg/kg, i.v., 4 times a day, 5 d) prolongs survival in mice with low inoculum of K. pneumoniae[3].
| Animal Model: | BALB/c low inoculum model of K. pneumoniae, KEN-11 strain[3]. |
| Dosage: | 100 mg/kg |
| Administration: | Intravenous injection (i.v.), 4 times a day, 5 d, in combination with Tazobactam (12.5 mg/kg, i.v., 4 times a day, 5 d) |
| Result: | Enabled all mice survived whereas all control mice died by 5 d, decreased the number of bacteria in lungs compared with control group. Observed no bacteria in the blood of most mice (except for two mice at the early phase) while bacteria were observed in the blood of control group. Observed few inflammatory cells in the alveoli whereas an influx of numerous inflammatory cells were observed in the control group. |
PIPERACILLINSupplier
Sinopharm Chemical Reagent Co,Ltd.
- Tel
- 86-21-63210123
- sj_scrc@sinopharm.com
Beijing HuaMeiHuLiBiological Chemical
- Tel
- 010-56205725
- waley188@sohu.com
Finetech Industry Limited
- Tel
- 027-87465837 19945049750
- sales@finetechnology-ind.com
Alta Scientific Co., Ltd.
- Tel
- 022-6537-8550 15522853686
- sales@altasci.com.cn
Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel
- +86-400-002-6226 +86-13028896684;
- sales@rrkchem.com