ANISODAMINE Chemical Properties

Melting point:

62-63 °C

Boiling point:

474.6±45.0 °C(Predicted)

Density 

1.27

storage temp. 

room temp

solubility 

H2O: ≥5mg/mL

pka

14.12±0.10(Predicted)

form 

powder

color 

white to beige

Safety Information

WGK Germany 

3

ANISODAMINE Usage And Synthesis

Uses

6S-Hydroxyhyoscyamine is a derivative of Hyoscyamine (H674300), a natural compound that has inhibitory activity against cholinesterases.

General Description

Racemic mixture of diastereomers.

Biochem/physiol Actions

Anisodamine is a non‐specific cholinergic antagonist. It is considered less efficient and less toxic than atropine. Anisodamine interferes with liposome structure and affects cell membrane. It might act as an anti‐oxidant, in protecting against the damage caused by free radicals. Anisodamine is known to reduce cardiac conduction and also prevents arrhythmia. It can block thromboxane synthesis and might possess anti‐thrombotic function. Anisodamine has been useful in a number therapies including septic shock, circulatory disorders, organophosphorus poisoning, opiate addiction, snake bite and radiation damage. Disorders, such as migraine, gastric ulcers, rheumatoid arthritis, gastrointestinal colic, eclampsia, respiratory diseases, acute glomerular nephritis and obstructive jaundice can be treated with the help of anisodamine.

ANISODAMINE(55869-99-3)Related Product Information

• ANISODAMINE HYDROBROMIDE
• Anisodamine
• Racanisodamine
• Raceanisodamine impurity
• 6-hydroxy-8-methyl-8-aza-bicyclo(3.2.1)octan-3-y1 2-phenylacrylate
• HYOSCINE HYDROCHLORIDE
• Tropinone
• Atropine
• littorine
• (S)-Tropic acid
• Pseudotropine
• (1R,2R,4S,5S,7s,9S)-7-(((S)-3-hydroxy-2-phenylpropanoyl)oxy)-9-methyl-9-propyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium
• endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl (hydroxymethyl)phenylacetate
• Atropine-d5
• Atropine sulfate
• Noratropine
• (R)-2-Phenyl-3-hydroxypropionic acid
• APOATROPINE