4-Bromo-3-fluorotoluene Chemical Properties

Boiling point:

95 °C/50 mmHg (lit.)

Density 

1.494 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.53(lit.)

Flash point:

95 °F

storage temp. 

Sealed in dry,Room Temperature

form 

Liquid

Specific Gravity

1.494

color 

Clear light yellow

BRN 

2500154

CAS DataBase Reference

452-74-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

26-37/39-16

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

3

PackingGroup 

III

HS Code 

29039990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Bromo-3-fluorotoluene Usage And Synthesis

Chemical Properties

colorless to light yellow liqui

Uses

4-Bromo-3-fluorotoluene may be used in the preparation of 1-(4-cyano-3- fluorobenzyl)-5-imidazolecarboxaldehyde and 1-bromo-4-bromomethyl-2-fluorobenzene.

Uses

4-Bromo-3-fluorotoluene is used in the synthesis of S-trityl-L-cysteine based inhibitors that show potent antitumor activity in lung cancer models. Chemical reagent for organic synthesis.

General Description

4-Bromo-3-fluorotoluene (1-bromo-2-fluoro-4-methylbenzene) is an aryl fluorinated building block. Synthesis of 4-bromo-3-fluorotoluene from o-nitro-p-toluidine (Fast Red Base GL), via diazo reaction at high temperature, Sandmeyer reaction, reduction and Schiemann reaction has been reported. Its density and refractive index have been determined.

4-Bromo-3-fluorotoluene(452-74-4)Related Product Information

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