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Cinepazide

Basic information Safety Supplier Related

Cinepazide Basic information

Product Name:
Cinepazide
Synonyms:
  • CINEPAZIDE
  • 1-(pyrrolidin-1-ylcarbonylmethyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine
  • PIPERAZINE,1-[2-OXO-2-(1-PYRROLIDINYL)ETHYL]-4-[1-OXO-3-(3,4,5-TRIMETHOXYPHENYL)-2-PROPENYL]
  • 1-(1-Pyrrolidinylcarbonylmethyl)-4-[3-(3,4,5-trimethoxyphenyl)acryloyl]piperazine
  • 1-[(1-Pyrrolidinylcarbonyl)methyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]piperazine
  • 2-Propen-1-one, 1-[4-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1-piperazinyl]-3-(3,4,5-trimethoxyphenyl)-
  • Cinepazide USP/EP/BP
  • Cinepazide free base
CAS:
23887-46-9
MF:
C22H31N3O5
MW:
417.5
EINECS:
245-928-9
Mol File:
23887-46-9.mol
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Cinepazide Chemical Properties

Boiling point:
637.8±55.0 °C(Predicted)
Density 
1.200±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
5.22±0.10(Predicted)
CAS DataBase Reference
23887-46-9(CAS DataBase Reference)
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Cinepazide Usage And Synthesis

Uses

Cinepazide is an injection in the treatment of acute myocardial infarction and its effect on serum inflammatory factors.

Definition

ChEBI: Cinepazide is an olefinic compound. It is functionally related to a cinnamic acid.

World Health Organization (WHO)

Cinepazide, a vasodilating agent, was first introduced into medicine in 1974. It is used in the treatment of peripheral and cerebral vascular disorders. Following reports of blood dyscrasias, including agranulocytosis and thrombocytopenia, associated with the use of the drug, the Spanish Committee on Drug Surveillance has recommended its withdrawal. In other countries, the approved product information of preparations containing cinepazide has been amended to include a relevant warning on these adverse effects.

CinepazideSupplier

LGM Pharma
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LETOPHARM LIMITED
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