Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Biochemical Engineering >  Chinese Herbs >  GUAYEWUANINE B

GUAYEWUANINE B

Basic information Safety Supplier Related

GUAYEWUANINE B Basic information

Product Name:
GUAYEWUANINE B
Synonyms:
  • YUNACONITINE
  • ISOACONITINE
  • GUAYEWUANINE B
  • JESACONITINE
MF:
C35H49NO12
MW:
675.76
Mol File:
Mol File
More
Less

GUAYEWUANINE B Chemical Properties

Melting point:
128-131°C
More
Less

GUAYEWUANINE B Usage And Synthesis

Description

A aconite alkaloid present in Aconitum fischeri Reich, A. sachalinense, Fr. Schmidt (Saghalien) and A. subcuneaturn, Nakai, this base is amorphous but yields crystalline salts, e.g. the perchlorate, m.p. 230-2°C (dec.); aurich10ride, m.p. 208-9°C (dec.) and a perbromide, m.p. 181-2°C (dec.). Boiling dilute H2S04 causes hydrolysis with the production of acetic acid and jesanisaconine (p-anisoylaconine) forming a crystalline hydrochloride, m.p. 209- 21 O°C (dec.).Alkaline hydrolysis gives acetic and p-anisic acids and aconine. Pyrolysis furnishes pyrojesaconitine, obtained as the crystalline perchlorate, m.p. 171-2°C; [α]13D - 27.4° (MeOH). Oxidation with KMn04 yields acetaldehyde, indicative of an ethylimino group. The structure of the alkaloid has been determined by con_x0002_tinuous monitoring of the pyrolysis and an examination of the products produced.
Jesaconitine is, like all of the aconitines, highly toxic producing raspiratory paralysis and a direct toxic action on the heart, the latter often terminating in ventricular fibrillation.

Occurrence

A complex aconitine alkaloid, yunaconitine has been isolated from Aconitum hemsJeyanum.

References

Makoshi., Arch. Pharm., 247,243 (1909)
Majima, Suginome, Morio., Ber., 57B, 1486 (1924)
Majima, Morio.,Annalen., 476,171,194,203 (1929)
Tamura., ibid, 533,183 (1937)
Structure:
Keith, Pelletier., Chem. Commun., 993 (1967)
Keith, Pelletier., ibid, 161 (1968)
Keith, Pelletier., 1. Org. Chem., 33, 2497 (1968)

GUAYEWUANINE BSupplier

Scandinavian Formulas
Tel
800-688-2276
Email
mikep@scandinavianformulas.com
United States Biological
Tel
800.520.3011 or 781.639.5092
Email
chemicals@usbio.net
Shanghai Xuanya Biotechnology Co., Ltd.
Tel
021-62457717
Email
1517347860@qq.com
Shanghai Yuanmu Biological Technology Co., Ltd.
Tel
021-58322859
Guangzhou Weijia Technology Co., Ltd.
Tel
020-84224925 18300190102
Email
WHIGA22@126.COM
More
Less

GUAYEWUANINE B()Related Product Information