2-Methyl-3-nitrobenzoic acid Chemical Properties

Melting point:

182-184 °C (lit.)

Boiling point:

314.24°C (rough estimate)

Density 

1.4283 (rough estimate)

refractive index 

1.5468 (estimate)

storage temp. 

Sealed in dry,Room Temperature

form 

powder to crystal

pka

3.03±0.20(Predicted)

color 

White to Light red to Green

Water Solubility 

<0.1 g/100 mL at 22 ºC

BRN 

2050096

InChIKey

YPQAFWHSMWWPLX-UHFFFAOYSA-N

CAS DataBase Reference

1975-50-4(CAS DataBase Reference)

EPA Substance Registry System

2-Methyl-3-nitrobenzoic acid (1975-50-4)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36-36/37/39-22

WGK Germany 

3

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29163900

MSDS

• Language:English Provider:2-Methyl-3-nitrobenzoic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Methyl-3-nitrobenzoic acid Usage And Synthesis

Chemical Properties

white crystal powder

Uses

3-Nitro-o-toluic Acid, is a building block used for the synthesis of various compounds. It is an intermediate for the synthesis of 4-(Piperazin-1-ylmethyl)-N1-arylsulfonyl indole derivatives as 5-HT6 receptor ligands.

Uses

2-Methyl-3-nitrobenzoic acid was used as starting reagent in the synthesis of methyl 2-methyl-3-nitrobenzoate and 2,3-unsubstituted indoles.

General Description

Fine needles or light beige powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Methyl-3-nitrobenzoic acid is a nitrated carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.

Fire Hazard

Flash point data for 2-Methyl-3-nitrobenzoic acid is not available. 2-Methyl-3-nitrobenzoic acid is probably combustible.

2-Methyl-3-nitrobenzoic acid(1975-50-4)Related Product Information

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• Methyl