1-Benzyl-4-hydroxypiperidine Chemical Properties

Melting point:

61-63 °C(lit.)

Boiling point:

127-128 °C2 mm Hg(lit.)

Density 

1.0096 (rough estimate)

refractive index 

1.5212 (estimate)

Flash point:

121-123°C/0.7mm

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform, Methanol

pka

14.87±0.20(Predicted)

form 

Crystalline Powder

color 

White to yellow

Sensitive 

Hygroscopic

BRN 

146118

CAS DataBase Reference

4727-72-4(CAS DataBase Reference)

NIST Chemistry Reference

4-Piperidinol, 1-(phenylmethyl)-(4727-72-4)

Safety Information

Hazard Codes 

T,C,Xi,Xn

Risk Statements 

25-36/37/38-20/21/22

Safety Statements 

26-45-37/39-36

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

2

HS Code 

29333990

MSDS

• Language:English Provider:1-Benzyl-4-hydroxypiperidine
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1-Benzyl-4-hydroxypiperidine Usage And Synthesis

Chemical Properties

WHITE TO YELLOWISH CRYSTALLINE POWDER

Uses

A piperidine based pesticide

Uses

1-Benzyl-4-hydroxypiperidine was used as an alternative molecule to study the ligand concentration attached to the epoxy-activated Sepharose 6B.

Uses

1-Benzyl-4-hydroxypiperidine is the reactant for synthesis of: Muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist1 Fatty acid amide hydrolase inhibitors PI3 kinase-alpha inhibitors Flavonoid derivatives used as dual binding acetylcholinesterase inhibitors Urotensin-II receptor antagonists Rho kinase inhibitors.

Synthesis Reference(s)

Journal of the American Chemical Society, 108, p. 3512, 1986 DOI: 10.1021/ja00272a059

1-Benzyl-4-hydroxypiperidine(4727-72-4)Related Product Information

• N-Benzyl-4-piperidone
• Benzyl chloride
• Haloperidol
• Benzyltrimethylammonium chloride
• Benzyltriethylammonium chloride
• 4-Cyanophenol
• DROPERIDOL
• Benzyl alcohol
• N-Benzylglycine
• Ethyl N-benzyl-3-oxo-4-piperidine-carboxylate hydrochloride
• Diphenoxylate
• Benzyl
• 4-Hydroxypiperidine
• butropium bromide
• 1-benzyl-4-hydroxypiperidine-4-carbonitrile
• benzyl 3-hydroxypiperidine-1-carboxylate
• BENZYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE
• 1-BENZYL-3-HYDROXYPIPERIDINE HYDROCHLORIDE