(4-BROMO-2-NITRO-PHENYL)-ACETIC ACID Chemical Properties

Melting point:

156-160

Boiling point:

392.0±27.0 °C(Predicted)

Density 

1.794

storage temp. 

Sealed in dry,Room Temperature

pka

3.81±0.10(Predicted)

Appearance

White to off-white Solid

Safety Information

Hazard Codes 

Xi

Hazard Note 

Irritant

HS Code 

2916399090

(4-BROMO-2-NITRO-PHENYL)-ACETIC ACID Usage And Synthesis

Uses

4-Bromo-2-nitrophenylacetic acid is used in the preparation and structure-activity relations of GNF-5837 derivatives, which are selective TRK inhibitors with efficacy in rodent cancer tumor models

References

[1] Patent: WO2008/73480, 2008, A1. Location in patent: Page/Page column 27-28
[2] Patent: EP2108641, 2009, A1. Location in patent: Page/Page column 29
[3] Patent: EP2113503, 2009, A1. Location in patent: Page/Page column 21
[4] Patent: US2003/69421, 2003, A1
[5] Patent: US6486185, 2002, B1

(4-BROMO-2-NITRO-PHENYL)-ACETIC ACID(6127-11-3)Related Product Information

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