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ATRACTYLOSIDE POTASSIUM SALT

Basic information Safety Supplier Related

ATRACTYLOSIDE POTASSIUM SALT Basic information

Product Name:
ATRACTYLOSIDE POTASSIUM SALT
Synonyms:
  • ATR, 2K
  • ATRACTYLOSIDE, DIPOTASSIUM SALT
  • ATRACTYLOSIDE, DIPOTASSIUM SALT, ATRACTYLIS GUMMIFERA
  • ATRACTYLOSIDE POTASSIUM SALT
  • 19-Norkaur-16-en-18-oic acid, 15-hydroxy-2-2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-.beta.-D-glucopyranosyloxy-, dipotassium salt, (2.beta.,15.alpha.)-
  • (2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]-19-norkaur-16-en-18-oic acid dipotassium salt
  • 19-Norkaur-16-en-18-oicacid, 15-hydroxy-2-[[2-O-(3-Methyl-1-oxobutyl)-3,4-di-O-sulfo-b-D-glucopyranosyl]oxy]-,dipotassiuM salt, (2b,15a)- (9CI)
  • Atractyloside dipotassium salt, >=98%
CAS:
102130-43-8
MF:
C30H47KO16S2
MW:
766.91
Product Categories:
  • reagent
  • standard substance
  • chemical reagent
  • herbal extract
  • pharmaceutical intermediate
  • phytochemical
  • Cell Stress
  • Mitochondrial Inhibitors
  • Nitric Oxide and Cell Stress
  • reference standards from Chinese medicinal herbs (TCM).
Mol File:
102130-43-8.mol
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ATRACTYLOSIDE POTASSIUM SALT Chemical Properties

Melting point:
234-238°C
storage temp. 
Sealed in dry,2-8°C
solubility 
H2O: 20 mg/mL
form 
Solid
color 
Pale Brown to Pale Beige
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
T
Risk Statements 
23/24/25
Safety Statements 
36/37-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
HazardClass 
6.1(a)
PackingGroup 
I
HS Code 
2938909090

MSDS

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ATRACTYLOSIDE POTASSIUM SALT Usage And Synthesis

Description

Atractyloside is a natural heteroglucoside produced in some plants, including A. gummifera. Atractyloside prevents mitochondrial ATP synthesis by inhibiting ADP/ATP translocases, which are responsible for the exchange of adenine di- and triphosphates across the inner mitochondrial membrane.

Uses

Atractyloside Dipotassium Salt is an inhibitor of ANT and apoptosis inducer.

References

[1]. yamaguchi n, kagari t, kasai m. inhibition of the ryanodine receptor calcium channel in the sarcoplasmic reticulum of skeletal muscle by an adp/atp translocase inhibitor, atractyloside. biochem biophys res commun, 1999, 258(2): 247-251.
[2]. pick-kober kh, schneider f. proliferation, macromolecular synthesis and energy metabolism of in vitro grown ehrlich ascites tumor cells after inhibition of atp-adp translocation by atractyloside. eur j cell biol, 1984, 34(2): 323-329.
[3]. malekova l, kominkova v, ferko m, et al. bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. biochim biophys acta, 2007, 1767(1): 31-44.

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