ATRACTYLOSIDE POTASSIUM SALT
ATRACTYLOSIDE POTASSIUM SALT Basic information
- Product Name:
- ATRACTYLOSIDE POTASSIUM SALT
- Synonyms:
-
- ATR, 2K
- ATRACTYLOSIDE, DIPOTASSIUM SALT
- ATRACTYLOSIDE, DIPOTASSIUM SALT, ATRACTYLIS GUMMIFERA
- ATRACTYLOSIDE POTASSIUM SALT
- 19-Norkaur-16-en-18-oic acid, 15-hydroxy-2-2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-.beta.-D-glucopyranosyloxy-, dipotassium salt, (2.beta.,15.alpha.)-
- (2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]-19-norkaur-16-en-18-oic acid dipotassium salt
- 19-Norkaur-16-en-18-oicacid, 15-hydroxy-2-[[2-O-(3-Methyl-1-oxobutyl)-3,4-di-O-sulfo-b-D-glucopyranosyl]oxy]-,dipotassiuM salt, (2b,15a)- (9CI)
- Atractyloside dipotassium salt, >=98%
- CAS:
- 102130-43-8
- MF:
- C30H47KO16S2
- MW:
- 766.91
- Product Categories:
-
- reagent
- standard substance
- chemical reagent
- herbal extract
- pharmaceutical intermediate
- phytochemical
- Cell Stress
- Mitochondrial Inhibitors
- Nitric Oxide and Cell Stress
- reference standards from Chinese medicinal herbs (TCM).
- Mol File:
- 102130-43-8.mol
ATRACTYLOSIDE POTASSIUM SALT Chemical Properties
- Melting point:
- 234-238°C
- storage temp.
- Sealed in dry,2-8°C
- solubility
- H2O: 20 mg/mL
- form
- Solid
- color
- Pale Brown to Pale Beige
- Stability:
- Hygroscopic
MSDS
- Language:English Provider:SigmaAldrich
ATRACTYLOSIDE POTASSIUM SALT Usage And Synthesis
Description
Atractyloside is a natural heteroglucoside produced in some plants, including A. gummifera. Atractyloside prevents mitochondrial ATP synthesis by inhibiting ADP/ATP translocases, which are responsible for the exchange of adenine di- and triphosphates across the inner mitochondrial membrane.
Uses
Atractyloside Dipotassium Salt is an inhibitor of ANT and apoptosis inducer.
References
[1]. yamaguchi n, kagari t, kasai m. inhibition of the ryanodine receptor calcium channel in the sarcoplasmic reticulum of skeletal muscle by an adp/atp translocase inhibitor, atractyloside. biochem biophys res commun, 1999, 258(2): 247-251.
[2]. pick-kober kh, schneider f. proliferation, macromolecular synthesis and energy metabolism of in vitro grown ehrlich ascites tumor cells after inhibition of atp-adp translocation by atractyloside. eur j cell biol, 1984, 34(2): 323-329.
[3]. malekova l, kominkova v, ferko m, et al. bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. biochim biophys acta, 2007, 1767(1): 31-44.
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