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2,4-Dichlorobenzyl chloride

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2,4-Dichlorobenzyl chloride Basic information

Product Name:
2,4-Dichlorobenzyl chloride
Synonyms:
  • 2,4-dichloro-1-(chloromethyl)-benzen
  • 2,4-Dichloro-1-(chloromethyl)benzene
  • 2,4-dichloro-1-chloromethyl-benzene
  • -2,4-Trichlorotoluene
  • benzene,2,4-dichloro-1-(chloromethyl)-
  • Toluene, alpha2,4-trichloro-
  • toluene,α,2,4-trichloro-
  • α,2,4-trichlorotoluene
CAS:
94-99-5
MF:
C7H5Cl3
MW:
195.47
EINECS:
202-381-0
Product Categories:
  • Aromatics
  • Miscellaneous Reagents
  • Econazole Nitrate
  • Aromatic Halides (substituted)
Mol File:
94-99-5.mol
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2,4-Dichlorobenzyl chloride Chemical Properties

Melting point:
-2.6 °C (lit.)
Boiling point:
248 °C (lit.)
Density 
1.407 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.576(lit.)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Oily Liquid
color 
Clear colorless to very light yellow
BRN 
387220
InChI
InChI=1S/C7H5Cl3/c8-4-5-1-2-6(9)3-7(5)10/h1-3H,4H2
InChIKey
IRSVDHPYXFLLDS-UHFFFAOYSA-N
SMILES
C1(CCl)=CC=C(Cl)C=C1Cl
LogP
4.08
CAS DataBase Reference
94-99-5(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 2,4-dichloro-1-(chloromethyl)-(94-99-5)
EPA Substance Registry System
Benzene, 2,4-dichloro-1-(chloromethyl)- (94-99-5)
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Safety Information

Hazard Codes 
C,N
Risk Statements 
34-37-50/53-22
Safety Statements 
26-36/37/39-45-61-60
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
19
Hazard Note 
Corrosive
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29036990

MSDS

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2,4-Dichlorobenzyl chloride Usage And Synthesis

Chemical Properties

clear colorless to very light yellow oily liquid

Uses

2,4-Dichlorobenzyl chloride was used as starting reagent for the synthesis of series of novel 1,2,4-triazolium derivatives.

Uses

2,4-Dichlorobenzyl chloride is a reagent used in the addition of dichlorobenzene.

Synthesis

1777-82-8

94-99-5

GENERAL STEPS: 2,4-dichlorobenzyl alcohol (17.7 g, 0.1 mol), dichloromethane (30 mL), and N,N-dimethylformamide (DMF, 1 mL) were added to a 100 mL round-bottomed flask, followed by the slow dropwise addition of phosphorus trichloride (4.68 g, 0.034 mol). The reaction mixture was heated to reflux temperature (60-80°C) and the reaction lasted for 2-3 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) until the complete disappearance of the raw material. After completion of the reaction, 2,4-dichlorobenzyl chloride (17.99 g, 92% yield) was purified by distillation.

References

[1] Patent: CN106117028, 2016, A. Location in patent: Paragraph 0053; 0054; 0055; 0056

2,4-Dichlorobenzyl chloride Preparation Products And Raw materials

Preparation Products

Raw materials

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