2-Pyridylacetonitrile Chemical Properties

Melting point:

23-25°C

Boiling point:

76-77 °C/2 mmHg (lit.)

Density 

1.059 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.525(lit.)

Flash point:

201 °F

solubility 

soluble in Chloroform, Methanol

pka

3.22±0.12(Predicted)

form 

powder to lump to clear liquid

color 

White or Colorless to Yellow to Orange

Water Solubility 

Miscible with water.

BRN 

111215

CAS DataBase Reference

2739-97-1(CAS DataBase Reference)

NIST Chemistry Reference

2-Pyridylacetonitrile(2739-97-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

UN 3276 6.1/PG 3

WGK Germany 

3

F 

2-8-9

HazardClass 

6.1

PackingGroup 

III

HS Code 

29333990

MSDS

• Language:English Provider:2-(2-Pyridyl)acetonitrile
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Pyridylacetonitrile Usage And Synthesis

Chemical Properties

Colorless to yellow to orange to brown liquid

Uses

2-Pyridineacetonitrile is used as a pharmaceutical intermediate. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

General Description

2-Pyridylacetonitrile undergoes coupling with aromatic diazonium salts to yield arylhydrazones. It also undergoes condensation with active malonic esters to yield 1-cyano-3-substituted 2-hydroxyquinolizin-4-ones. Acylation reaction of 2-pyridylacetonitrile with hot acetic anhydride has been reported.

2-Pyridylacetonitrile(2739-97-1)Related Product Information

• 2-Chloro-3-cyanopyridine
• Pyridine
• Iminodiacetonitrile
• 2,6-Lutidine
• Benzeneacetonitrile
• acetonitrile
• Glycolonitrile
• 2-(6-CHLORO-3-PYRIDAZINYL)-2-(2-PYRIDINYL)ACETONITRILE
• A-PHENYL-2-PYRIDYLACETONITRILE,PHENYL-2-PYRIDYLACETONITRILE,1-Phenyl-1-(2-pyridylacetonitrile)
• 4-(DIISOPROPYLAMINO)-2-PHENYL-2-(2-PYRIDYL)-BUTYRONITRILE
• 3-PYRIDYLACETONITRILE
• 4-PYRIDYLACETONITRILE HCL,4-Pyridylacetonitrile HCl Salt,4-PYRIDYLACETONITRILE HYDROCHLORIDE,4-PYRIDYLACETONITRILE MONOHYDROCHLORIDE
• 2-Chloro-5-pyridineacetonitrile
• 4-Pyridinepropanenitrile
• 2-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-(4-NITROPHENYL)ACETONITRILE
• 2-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-(4-METHOXYPHENYL)ACETONITRILE
• 2-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-PHENYLACETONITRILE
• 2-(4-CHLOROPHENYL)-2-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]ACETONITRILE